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- Title
The long-term stability of the insulin test after partial vagotomy in the dog.
- Authors
Spencer, John; Stening, G. Frank
- Abstract
Five dogs were prepared with gastric fistulae, and partial vagotomy was performed by division of one vagus in the neck and a main vagal trunk in the lower thorax. The acid secretory responses to histamine dihydrochloride (o.16 mg. per kg.-hr.), and to graded intravenous doses of insulin (0.03, 0.06, 0.12, 0.5, and 1 U. per kg.) were measured soon after vagotomy and again 6 months later. There was no significant change in the acid response to either histamine or insulin during the 6 months after vagotomy either in timing of the peak output or in the dose of insulin required for highest peak acid output. It is concluded that no detectable reinnervation occurs in the dog in this period following gastric vagotomy.
- Publication
British Journal of Surgery, 1971, Vol 58, Issue 7, p510
- ISSN
0007-1323
- Publication type
Article
- DOI
10.1002/bjs.1800580710