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- Title
Molecular functions of HAX1 during disease progress.
- Authors
Zhang, Dajun; Yang, Jinke; Huang, Qi; Zhao, Dengshuai; Wang, Tianyu; Yu, Dixi; Qin, Limei; Zhang, Keshan
- Abstract
HCLS1-associated protein X-1 (HAX1) is a newly discovered multifunctional cell regulatory protein that is widely expressed in cells and has a close relationship with multiple cellular proteins. HAX1 plays important roles in various processes, including the regulation of apoptosis, maintenance of mitochondrial membrane potential stability and calcium homeostasis, occurrence and development of diseases, post-transcriptional regulation of gene expression, and host immune response after viral infection. In this article, we have reviewed the research progress on the biological functions of HAX1, thereby laying a theoretical foundation for further exploration of its underlying mechanisms and targeted application.
- Subjects
GENETIC regulation; MEMBRANE potential; VIRUS diseases; APOPTOSIS; HOMEOSTASIS
- Publication
Virus Genes, 2024, Vol 60, Issue 5, p435
- ISSN
0920-8569
- Publication type
Article
- DOI
10.1007/s11262-024-02081-8