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- Title
Structure-activity relationship in advanced glycation end products formation inhibitory activity of phlorotannins.
- Authors
Mitsuhiro Sekiguchi; Seiya Shinoda; Uno, Arisa; Tomoya Masaki; Tetsuya Sasaki; Haruaki Ishiyama
- Abstract
The structure and inhibitory activity of advanced glycation end products (AGEs) formation were studied using six model compounds and seven phlorotannins isolated from brown alga Ecklonia stolonifera. As a result, it was inferred that AGEs formation inhibitory activity was stronger when electron-rich groups were present because of the addition of many oxygen atoms to the phlorotannins.
- Subjects
ADVANCED glycation end-products; RECEPTOR for advanced glycation end products (RAGE); STRUCTURE-activity relationships; BROWN algae
- Publication
Bioscience, Biotechnology & Biochemistry, 2022, Vol 86, Issue 9, p1207
- ISSN
0916-8451
- Publication type
Article
- DOI
10.1093/bbb/zbac106