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- Title
The human bitter taste receptor hTAS2R39 is the primary receptor for the bitterness of theaflavins.
- Authors
Toyomi Yamazaki; Miki Sagisaka; Riko Ikeda; Toshiyuki Nakamura; Noriko Matsuda; Takeshi Ishii; Tsutomu Nakayama; Tatsuo Watanabe
- Abstract
The article discusses a study on the responses of hTAS2Rs to 4 major teaflavins based on the theory that the bitterness of theaflavins (TFs) may be sensed through hTAS2R39 and hTAS2R14. hTAS2R and Ga16gust44 were transfected into Flp-In G cells using Lipofectamine 2000 and the cells were incubated for 60 min with 3uM Fluo-8AM. It suggests that the human threshold of bitterness perception can be higher than that of a cell-based assay.
- Subjects
FLAVINS; BITTERNESS (Taste); CELLS; TASTE receptors; BIOLOGICAL pigments
- Publication
Bioscience, Biotechnology & Biochemistry, 2014, Vol 78, Issue 10, p1753
- ISSN
0916-8451
- Publication type
Article
- DOI
10.1080/09168451.2014.930326