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- Title
Mixed inhibitions by methanol, furfural and acetic acid on xylitol production by Candida guilliermondii.
- Authors
Converti, Attilio; Perego, Patrizia; Torre, Paolo; da Silva, Silvio Silverio
- Abstract
Xylose production by Candida guilliermondii FTI 20037 was carried out in a synthetic medium in the presence of 0–100 g methanol l-1, 0–0.7 g furfural l-1 or 0–1.3 g acetic acid l-1. Kinetic results show a mixed inhibition mechanism in all three cases. Maximum specific productivity and saturation constant for product formation were, in the absence of inhibition, 3.6 gP gX-1 h-1 and 232 gS l-1, respectively, while the inhibition constants, Ki and Ki′, were 17 and 50 g methanol l-1, 0.62 and 7.0 g furfural l-1, 0.69 and 3.5 g acetic acid l-1, which suggests the following order of inhibition: furfural > acetic acid > methanol.
- Subjects
XYLITOL; CANDIDA; METHANOL; ACETIC acid; FURFURAL; FATTY acids
- Publication
Biotechnology Letters, 2000, Vol 22, Issue 23, p1861
- ISSN
0141-5492
- Publication type
Article
- DOI
10.1023/A:1005605210325