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- Title
Zotepine in Huntington's disease.
- Authors
Raphael M. Bonelli; Gerald Niederwieser; Theresa Lahousen; Peter Hofmann
- Abstract
The authors report a patient with Huntington's disease (HD) presenting with severe chorea. The motor scale of the unified HD rating scale (UHDRS-I) revealed 81 points. Motor function clearly improved with zotepine, until she reached an UHDRS-I of 34 points on day 7 of treatment. The patient was stable for at least 12 weeks. The improvement includes all seven categories of the UHDRS-I, especially chorea, gait and oral function. This is the first description of zotepine in HD. Our findings suggest that zotepine is useful in the treatment of HD chorea. Controlled trials of its use in HD would be welcome. Copyright © 2003 John Wiley & Sons, Ltd.
- Subjects
HUNTINGTON disease; GENETIC disorders; PSYCHIATRIC rating scales; PSYCHODIAGNOSTICS; PSYCHOLOGY
- Publication
Human Psychopharmacology: Clinical & Experimental, 2003, Vol 18, Issue 3, p227
- ISSN
0885-6222
- Publication type
Article
- DOI
10.1002/hup.474