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- Title
Doppler flowmetry of the superior mesenteric artery and portal vein: impact for the early prediction of necrotizing enterocolitis in neonates.
- Authors
Urboniene, Ausra; Palepsaitis, Arvydas; Uktveris, Rimantas; Barauskas, Vidmantas
- Abstract
<bold>Purpose: </bold>Necrotizing enterocolitis (NEC) is a serious gastrointestinal disorder in newborns. Early diagnosis and rapid treatment is essential for seeking good outcome for neonates. The aim of our study was to evaluate intestinal blood flow in superior mesenteric artery (SMA) and portal vein (PV) in neonates with suspected or confirmed NEC and investigate the prognostic cut-off values to develop NEC.<bold>Methods: </bold>Doppler flowmetry of SMA and PV was performed for 62 newborns. Resistive (RI) and pulsatility (PI) indexes were measured in SMA as well as Volumetric blood flow (Vflow) in PV. ROC curves were applied to estimate sensitivity and specificity and to identify cut-off values.<bold>Results: </bold>There were 93.5% preterm neonates. 29 patients (46.8%) were diagnosed with NEC and 33 (53.2%) formed a control group. 96.3% NEC patients had RI >0.75 with sensitivity of 96.3% and specificity of 90.9% (OR 260). 88.9% NEC patients had PI >1.85 with sensitivity of 88.9% and specificity of 78.8% (OR 29). Portal Vflow lower than 37 ml/min was present in 89.7% patients with NEC (OR 11.7).<bold>Conclusion: </bold>Intestinal blood flow Dopplerography can be a useful tool for diagnosing and predicting NEC.
- Subjects
NEONATAL necrotizing enterocolitis; PORTAL vein physiology; DOPPLER effect; MESENTERIC artery; GASTROINTESTINAL diseases; BLOOD flow; BLOOD flow measurement; CARDIOVASCULAR disease diagnosis; HEMODYNAMICS; PREMATURE infants; PREMATURE infant diseases; LONGITUDINAL method; PORTAL vein
- Publication
Pediatric Surgery International, 2015, Vol 31, Issue 11, p1061
- ISSN
0179-0358
- Publication type
journal article
- DOI
10.1007/s00383-015-3792-y