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- Title
Hypertrophic olivary degeneration in children after posterior fossa surgery. An underdiagnosed condition.
- Authors
Ballestero, Matheus Fernando Manzolli; Viana, Dinark Conceição; Teixeira, Thiago Lyrio; Santos, Marcelo Volpon; de Oliveira, Ricardo Santos
- Abstract
Background: Hypertrophic olivary degeneration (HOD) is a rare transsynaptic form of degeneration occurring after injury to the dentato-rubro-olivary pathway (“Guillain-Mollaret triangle”). The majority of studies have described HOD resulting from posterior fossa (PF) hemorrhage or infarction. HOD in patients undergoing PF surgery has not been well characterized. These lesions are rare and symptomatic children with HOD are even more uncommon. The purpose of this study was to evaluate HOD that develops after PF operations in children.Materials and methods: A literature review was carried out describing 37 pediatric cases of HOD in 13 articles. In addition, two new cases of our own experience were included.Conclusions: HOD is a rare complication related after PF tumors surgery and symptoms may be misdiagnosed with pediatric cerebellar mutism syndrome. Children with HOD usually do not develop palatal tremor but ataxia is common.
- Subjects
POSTERIOR cranial fossa; DEGENERATION (Pathology); HEMORRHAGE; NEUROSURGERY; PEDIATRIC surgery; SURGERY
- Publication
Child's Nervous System, 2018, Vol 34, Issue 3, p409
- ISSN
0256-7040
- Publication type
Article
- DOI
10.1007/s00381-017-3705-6