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- Title
Late Recurrence of a Prostatic Adenocarcinoma as a Solitary Splenic Metastasis.
- Authors
Compérat, Eva; Azzouzi, Abdel-Rahmène; Chartier-Kastler, Emmanuel; Ménégaux, Fabrice; Capron, Frédérique; Richard, François; Charlotte, Frédéric
- Abstract
Splenic metastases of solid tumors are exceptional. We report the firstcaseof an isolated splenic metastasis from prostate carcinoma, 5 years after radical prostatectomy. The splenic tumor was revealed by a pain and progressive increase in the serum prostate-specific antigen (PSA) level. Histology of the spleen showed an adenocarcinoma immunostained with cytokeratin and PSA markers. The patient remained asymptomatic and his serum PSA level was within normal limits 17 months after the splenectomy. This case suggests that splenic metastasis might be the result of the growth of an early blood-borne micrometastasis within the spleen after a period of clinical latency. Copyright © 2007 S. Karger AG, Basel
- Subjects
PROSTATE cancer; PROSTATE-specific antigen; TUMOR antigens; PROSTATECTOMY; SPLEEN diseases
- Publication
Urologia Internationalis, 2007, Vol 78, Issue 1, p86
- ISSN
0042-1138
- Publication type
Article
- DOI
10.1159/000096942