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- Title
心包剥离术对老年慢性缩窄性心包炎患者ANF与ET的影响.
- Authors
陈兴华; 张继倬; 韩露; 陈杰; 王宁
- Abstract
Objective: To investigate the effect of pericardiectomy on the level of atrial natriuretic peptide (ANP) and endothelin (ET) in elderly patients with chronic constrictive pericarditis. Methods: 66 cases of chronic constrictive pericarditis from our hospital were selected and randomly divided into the control group and the patients in experiment group with 33 cases in each group. Two groups were given corresponding treatment, the patients in control group were given corresponding drugs to increase the heart's contractility, and some vasodilator drugs, and the patients in experimental group underwent pericardiectomy. After the end of treatment, the level of ANF, ET and blood pressure and clinical therapeutic effect were detected and compared. Results: Compared with before treatment, after treatment the level of ANF ET, diastolic pressure and pulse pressure were decreased in two groups, and the systolic blood pressure was elevated (P<0.05); compared with the control group, the level of ANF, ET, diastolic pressure and pulse pressure was lower in experimental group, and the systolic blood pressure level was higher (P<0.05). After treatment, the total efficiency was higher in the experimental group than that of control group (P<0.05). Conclusion: The pericardiectomy can reduce the level of ANF ET, diastolic blood pressure and pulse pressure and elevate systolic blood pressure level, and has good clinical curative effect in the treatment of chronic constrictive pericarditis.
- Publication
Progress in Modern Biomedicine, 2016, Vol 16, Issue 16, p3070
- ISSN
1673-6273
- Publication type
Article
- DOI
10.13241/j.cnki.pmb.2016.16.018