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- Title
Racial/Ethnic Differences in Labor Outcomes with Prostaglandin Vaginal Inserts.
- Authors
Stephenson, Megan; Hawkins, J.; Pevzner, Leo; Powers, Barbara; Wing, Deborah
- Abstract
Objective: The aim of this study is to compare labor outcomes across race/ethnicity in women undergoing prostaglandin labor induction. Methods: Secondary analysis of misoprostol vaginal insert (MVI) trial, a double-blind, randomized, control trial of 1,308 patients comparing sustained release vaginal inserts containing dinoprostone 10 mg and misoprostol 50 mcg (MVI 50) or 100 mcg (MVI 100). Results: Achievement of active labor and induction failures were similar across race/ethnicity. Cesareans were performed less frequently in whites (29 %) and Hispanics (24.5 %) compared to blacks (32.7 %) (adjusted odds ratio (aOR) 0.87, 95 % confidence interval (CI) 0.47-0.97, p = 0.03 and aOR 0.86, 95 % CI 0.44-0.97, p = 0.03, respectively). When compared to blacks, whites were less likely to undergo cesarean for non-reassuring fetal heart rate tracing (aOR 0.41, 95 % CI 0.25-0.66, p = 0.0003), as were Hispanics (aOR 0.38, 95 % CI 0.22-0.65, p = 0.0004). Postpartum hemorrhage occurred more frequently in Hispanics (8.8 %) versus blacks (4.1 %) and whites (OR 2.27, 95 % CI 0.23-0.82, p = 0.02 and OR 3.69, 95 % CI 0.14-0.51, p < 0.0001, respectively). Birth weights of black infants were lower than whites ( p < 0.0001) and Hispanics ( p = 0.0003). Neonatal outcomes did not differ between groups. Conclusion: Differences in labor induction outcomes with prostaglandin labor induction exist based on race/ethnicity. Blacks delivered smaller babies, were more likely to undergo cesarean, and have cesareans performed for non-reassuring fetal heart tracing compared to other groups. Hispanics were more likely to experience postpartum hemorrhage compared to the other races.
- Publication
Journal of Racial & Ethnic Health Disparities, 2015, Vol 2, Issue 2, p149
- ISSN
2197-3792
- Publication type
Article
- DOI
10.1007/s40615-014-0058-7