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A 3D tri-culture system reveals that activin receptor-like kinase 5 and connective tissue growth factor drive human glomerulosclerosis.
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- Journal of Pathology, 2017, v. 243, n. 3, p. 390, doi. 10.1002/path.4960
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- Article
Generation of a Soluble Form of Human Endoglin Fused to Green Fluorescent Protein.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 20, p. 11282, doi. 10.3390/ijms222011282
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- Article
Author Correction: Deficiency of Axl aggravates pulmonary arterial hypertension via BMPR2.
- Published in:
- 2022
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- Publication type:
- Correction Notice
Deficiency of Axl aggravates pulmonary arterial hypertension via BMPR2.
- Published in:
- Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02531-1
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- Publication type:
- Article
Homozygous GDF2 nonsense mutations result in a loss of circulating BMP9 and BMP10 and are associated with either PAH or an "HHT‐like" syndrome in children.
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- Molecular Genetics & Genomic Medicine, 2021, v. 9, n. 12, p. 1, doi. 10.1002/mgg3.1685
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- Article
High concentrations of soluble endoglin can inhibit BMP9 signaling in non-endothelial cells.
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- Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-33352-3
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- Article
Inactivation of platelet-derived growth factor-BB following modification by ADP-ribosyltransferase.
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- British Journal of Pharmacology, 2001, v. 133, n. 8, p. 1219, doi. 10.1038/sj.bjp.0704187
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- Article
A rare homozygous missense GDF2 (BMP9) mutation causing PAH in siblings: Does BMP10 status contribute?
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- American Journal of Medical Genetics. Part A, 2023, v. 191, n. 1, p. 228, doi. 10.1002/ajmg.a.62996
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- Article
Selective enhancement of endothelial BMPR-II with BMP9 reverses pulmonary arterial hypertension.
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- Nature Medicine, 2015, v. 21, n. 7, p. 777, doi. 10.1038/nm.3877
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- Article
Transcript Analysis Reveals a Specific HOX Signature Associated with Positional Identity of Human Endothelial Cells.
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- PLoS ONE, 2014, v. 9, n. 3, p. 1, doi. 10.1371/journal.pone.0091334
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- Article
The Effect of Badger Culling on Breakdown Prolongation and Recurrence of Bovine Tuberculosis in Cattle Herds in Great Britain.
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- PLoS ONE, 2012, v. 7, n. 12, p. 1, doi. 10.1371/journal.pone.0051342
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- Publication type:
- Article
BMP-9 Induced Endothelial Cell Tubule Formation and Inhibition of Migration Involves Smad1 Driven Endothelin-1 Production.
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- PLoS ONE, 2012, v. 7, n. 1, p. 1, doi. 10.1371/journal.pone.0030075
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- Publication type:
- Article
Circulating Adrenomedullin Does Not Regulate Systemic Blood Pressure but Increases Plasma Prolactin after Intravenous Infusion in Humans: A Pharmacokinetic Study*.
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- Journal of Clinical Endocrinology & Metabolism, 1997, v. 82, n. 1, p. 95, doi. 10.1210/jcem.82.1.3656
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- Publication type:
- Article
Hypoxic Induction of Cox-2 Regulates Proliferation of Human Pulmonary Artery Smooth Muscle Cells.
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- American Journal of Respiratory Cell & Molecular Biology, 2002, v. 27, n. 6, p. 688, doi. 10.1165/rcmb.2002-0067OC
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- Publication type:
- Article
Differential Adrenomedullin Release and Endothelin Receptor Expression in Distinct Subpopulations of Human Airway Smooth-Muscle Cells.
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- American Journal of Respiratory Cell & Molecular Biology, 2001, v. 25, n. 3, p. 317, doi. 10.1165/ajrcmb.25.3.4399
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- Publication type:
- Article
Adrenomedullin Expression and Growth Inhibitory Effects in Distinct Pulmonary Artery Smooth Muscle Cell Subpopulations.
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- American Journal of Respiratory Cell & Molecular Biology, 2001, v. 24, n. 2, p. 170, doi. 10.1165/ajrcmb.24.2.4210
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- Publication type:
- Article
Circulating BMP9 Protects the Pulmonary Endothelium during Inflammation-induced Lung Injury in Mice.
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- 2021
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- Publication type:
- journal article
Bone Morphogenetic Protein 9 Is a Mechanistic Biomarker of Portopulmonary Hypertension.
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- 2019
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- Publication type:
- journal article
Bone morphogenetic protein receptor type II deficiency and increased inflammatory cytokine production. A gateway to pulmonary arterial hypertension.
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- 2015
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- Publication type:
- journal article
4PBA Restores Signaling of a Cysteine-substituted Mutant BMPR2 Receptor Found in Patients with Pulmonary Arterial Hypertension.
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- American Journal of Respiratory Cell & Molecular Biology, 2020, v. 63, n. 2, p. 160, doi. 10.1165/rcmb.2019-0321OC
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- Publication type:
- Article
Transforming Growth Factor-β<sub>1</sub> Represses Bone Morphogenetic Protein-Mediated Smad Signaling in Pulmonary Artery Smooth Muscle Cells via Smad3.
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- American Journal of Respiratory Cell & Molecular Biology, 2013, v. 49, n. 6, p. 1135, doi. 10.1165/rcmb.2012-0470OC
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- Publication type:
- Article
Assessing effects from four years of industry-led badger culling in England on the incidence of bovine tuberculosis in cattle, 2013–2017.
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- Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-49957-6
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- Publication type:
- Article
BMPR-II mutations promote pulmonary arterial hypertension via a hyperinflammatory response.
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- Clinical Medicine, 2015, v. 15, p. s15, doi. 10.7861/clinmedicine.15-3-s15
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- Publication type:
- Article
ATP13A3 variants promote pulmonary arterial hypertension by disrupting polyamine transport.
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- Cardiovascular Research, 2024, v. 120, n. 7, p. 756, doi. 10.1093/cvr/cvae068
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- Publication type:
- Article
Single-cell RNA sequencing profiling of mouse endothelial cells in response to pulmonary arterial hypertension.
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- Cardiovascular Research, 2022, v. 118, n. 11, p. 2519, doi. 10.1093/cvr/cvab296
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- Publication type:
- Article
Approaches to treat pulmonary arterial hypertension by targeting BMPR2: from cell membrane to nucleus.
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- Cardiovascular Research, 2021, v. 117, n. 11, p. 2309, doi. 10.1093/cvr/cvaa350
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- Publication type:
- Article
TNFα drives pulmonary arterial hypertension by suppressing the BMP type-II receptor and altering NOTCH signalling.
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- Nature Communications, 2017, v. 8, n. 1, p. 14079, doi. 10.1038/ncomms14079
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- Article
An emerging class of new therapeutics targeting TGF, Activin, and BMP ligands in pulmonary arterial hypertension.
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- Developmental Dynamics, 2023, v. 252, n. 3, p. 327, doi. 10.1002/dvdy.478
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- Publication type:
- Article
The lysosomal inhibitor, chloroquine, increases cell surface BMPR-II levels and restores BMP9 signalling in endothelial cells harbouring BMPR-II mutations.
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- Human Molecular Genetics, 2013, v. 22, n. 25, p. 5296, doi. 10.1093/hmg/ddt492
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- Publication type:
- Article
The lysosomal inhibitor, chloroquine, increases cell surface BMPR-II levels and restores BMP9 signalling in endothelial cells harbouring BMPR-II mutations.
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- Human Molecular Genetics, 2013, v. 22, n. 18, p. 3667, doi. 10.1093/hmg/ddt216
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- Publication type:
- Article
Connexin-mediated regulation of the pulmonary vasculature.
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- Biochemical Society Transactions, 2015, v. 43, n. 3, p. 524, doi. 10.1042/BST20150030
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- Article
Further description of bovine tuberculosis trends in the United Kingdom and the Republic of Ireland, 2003-2015.
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- Veterinary Record: Journal of the British Veterinary Association, 2018, v. 183, n. 23, p. 1, doi. 10.1136/vr.104718
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- Article
The transforming growth factor-β-bone morphogenetic protein type signalling pathway in pulmonary vascular homeostasis and disease.
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- Experimental Physiology, 2013, v. 98, n. 8, p. 1262, doi. 10.1113/expphysiol.2012.069104
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- Publication type:
- Article
Identification of rare sequence variation underlying heritable pulmonary arterial hypertension.
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- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-03672-4
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- Article
Identifying on admission patients likely to develop acute kidney injury in hospital.
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- 2019
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- Publication type:
- journal article
Failure of bone morphogenetic protein receptor trafficking in pulmonary arterial hypertension: potential for rescue.
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- Human Molecular Genetics, 2008, v. 17, n. 20, p. 3180, doi. 10.1093/hmg/ddn214
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- Publication type:
- Article
Functional analysis of bone morphogenetic protein type II receptor mutations underlying primary pulmonary hypertension.
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- Human Molecular Genetics, 2002, v. 11, n. 13, p. 1517, doi. 10.1093/hmg/11.13.1517
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- Publication type:
- Article
Characterisation and Molecular Identification of Adrenomedullin Binding Sites in the Rat Spinal Cord: A Comparison with Calcitonin Gene-Related Peptide Receptors.
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- Journal of Neurochemistry, 1996, v. 67, n. 5, p. 2172, doi. 10.1046/j.1471-4159.1996.67052172.x
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- Publication type:
- Article
An organ-on-chip model of pulmonary arterial hypertension identifies a BMPR2-SOX17-prostacyclin signalling axis.
- Published in:
- Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-04169-z
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- Publication type:
- Article
Assessing the effects of the first 2 years of industry-led badger culling in England on the incidence of bovine tuberculosis in cattle in 2013-2015.
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- Ecology & Evolution (20457758), 2017, v. 7, n. 18, p. 7213, doi. 10.1002/ece3.3254
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- Publication type:
- Article
Reduced circulating BMP9 and pBMP10 in hospitalized COVID‐19 patients.
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- Pulmonary Circulation, 2023, v. 13, n. 1, p. 1, doi. 10.1002/pul2.12192
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- Publication type:
- Article
Targeting translational read‐through of premature termination mutations in BMPR2 with PTC124 for pulmonary arterial hypertension.
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- Pulmonary Circulation, 2020, v. 10, n. 3, p. 1, doi. 10.1177/2045894020935783
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- Publication type:
- Article
Log-transformation improves the prognostic value of serial NT-proBNP levels in apparently stable pulmonary arterial hypertension.
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- Pulmonary Circulation, 2011, v. 1, n. 2, p. 244, doi. 10.4103/2045-8932.83450
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- Publication type:
- Article