We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Old age and underlying interstitial abnormalities are risk factors for development of ARDS after pleurodesis using limited amount of large particle size talc.
- Authors
Shinno, Yuki; Kage, Hidenori; Chino, Haruka; Inaba, Atsushi; Arakawa, Sayaka; Noguchi, Satoshi; Amano, Yosuke; Yamauchi, Yasuhiro; Tanaka, Goh; Nagase, Takahide
- Abstract
ABSTRACT Background and objective Talc pleurodesis is commonly performed to manage refractory pleural effusion or pneumothorax. It is considered as a safe procedure as long as a limited amount of large particle size talc is used. However, acute respiratory distress syndrome (ARDS) is a rare but serious complication after talc pleurodesis. We sought to determine the risk factors for the development of ARDS after pleurodesis using a limited amount of large particle size talc. Methods We retrospectively reviewed patients who underwent pleurodesis with talc or OK-432 at the University of Tokyo Hospital. Results Twenty-seven and 35 patients underwent chemical pleurodesis using large particle size talc (4 g or less) or OK-432, respectively. Four of 27 (15%) patients developed ARDS after talc pleurodesis. Patients who developed ARDS were significantly older than those who did not (median 80 vs 66 years, P = 0.02) and had a higher prevalence of underlying interstitial abnormalities on chest computed tomography (CT; 2/4 vs 1/23, P < 0.05). No patient developed ARDS after pleurodesis with OK-432. This is the first case series of ARDS after pleurodesis using a limited amount of large particle size talc. Conclusion Older age and underlying interstitial abnormalities on chest CT seem to be risk factors for developing ARDS after talc pleurodesis.
- Subjects
PLEURODESIS; PNEUMOTHORAX; PARTICLE size determination; RESPIRATORY distress syndrome; TALC
- Publication
Respirology, 2018, Vol 23, Issue 1, p55
- ISSN
1323-7799
- Publication type
Article
- DOI
10.1111/resp.13192