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- Title
Plantar shear stress in the diabetic foot: A systematic review and meta‐analysis.
- Authors
Jones, Alexander D.; De Siqueira, Jonathan; Nixon, Jane E.; Siddle, Heidi J.; Culmer, Peter R.; Russell, David A.
- Abstract
Aims: Diabetic foot ulceration (DFU) is a multifactorial process involving undetected, repetitive trauma resulting in inflammation and tissue breakdown. Shear stress forms a major part of plantar load, the aim of this review is to determine whether elevated shear stress results in ulceration. Methods: A systematic review of the Ovid Medline, EMBASE, CINAHL and Cochrane library databases was performed. Studies involving patients with diabetes who underwent plantar shear stress assessment were included. The primary outcome was plantar shear stress in patients with diabetes who had a current/previous DFU compared with those with no prior ulceration. Meta‐analysis was performed comparing shear stress between those with a current or previous DFU and those without, and those with diabetes and healthy controls. Results: The search strategy identified 1461 potentially relevant articles, 16 studies met the inclusion criteria, involving a total of 597 patients. Comparing shear stress between the current/previous DFU group and those without: Standardised mean difference (SMD) 0.62 (95% CI −0.01 to 1.25), in favour of greater shear stress within the DFU group, p = 0.05. Comparing shear stress between people with diabetes and healthy controls: 0.36 (95% CI −0.31 to 1.03), in favour of greater shear stress within the diabetes group, p = 0.29. Conclusion: This review suggests that that patients with diabetes and a history of ulceration exhibit greater shear stress than their ulcer‐free counterparts. This strengthens the premise that development of systems to measure shear stress may be helpful in DFU prediction and prevention.
- Subjects
CINAHL database; META-analysis; MEDICAL information storage &; retrieval systems; INFORMATION storage &; retrieval systems; MEDICAL databases; CONFIDENCE intervals; DIABETIC foot; SYSTEMATIC reviews; PHYSIOLOGIC strain; SHEAR (Mechanics); MEDLINE
- Publication
Diabetic Medicine, 2022, Vol 39, Issue 1, p1
- ISSN
0742-3071
- Publication type
Article
- DOI
10.1111/dme.14661