We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Cause-specific mortality by race in low-income Black and White people with Type 2 diabetes.
- Authors
Conway, B. N.; May, M. E.; Fischl, A.; Frisbee, J.; Han, X.; Blot, W. J.
- Abstract
Aim To investigate, with extended follow-up, cause-specific mortality among low-income Black and White Americans with Type 2 diabetes who have similar socio-economic status. Methods Black and White Americans aged 40-79 years with Type 2 diabetes ( n = 12 498) were recruited from community health centres as part of the Southern Community Cohort Study. Multivariable Cox analysis was used to estimate mortality hazard ratios and 95% CIs for subsequent cause-specific mortality, based on both underlying and contributing causes of death. Results During the follow-up (median 5.9 years), 13.3% of the study population died. The leading causes of death in each race were ischaemic heart disease, respiratory disorders, cancer, renal failure and heart failure; however, Blacks were at a lower risk of dying from ischaemic heart disease (hazard ratio 0.70, 95% CI 0.54-0.91) or respiratory disorders (hazard ratio 0.70, 0.53-0.92) than Whites but had higher or similar mortality attributable to renal failure (hazard ratio 1.57, 95% CI 1.02-2.40), heart failure (hazard ratio 1.47, 95% CI 0.98-2.19) and cancer (hazard ratio 0.87, 95% CI 0.62-1.22). Risk factors for each cause of death were generally similar in each race. Conclusions These findings suggest that the leading causes of death and their risk factors are largely similar among Black and White Americans with diabetes. For the two leading causes of death in each race, however, ischaemic heart disease and respiratory disorders, the magnitude of risk is lower among Black Americans and contributes to their higher survival rates.
- Subjects
UNITED States; HEART disease related mortality; LIPID analysis; BLACK people; CHRONIC kidney failure; CLINICS; CONFIDENCE intervals; ETHNIC groups; PATIENT aftercare; HYPOGLYCEMIC agents; INCOME; INSULIN; LONGITUDINAL method; LUNG diseases; MORTALITY; TYPE 2 diabetes; ORAL drug administration; POVERTY; RACE; SEPSIS; TUMORS; WHITE people; COMORBIDITY; DATA analysis; SOCIOECONOMIC factors; BODY mass index; HUMAN research subjects; PROPORTIONAL hazards models; PATIENT selection; DISEASE duration
- Publication
Diabetic Medicine, 2015, Vol 32, Issue 1, p33
- ISSN
0742-3071
- Publication type
Article
- DOI
10.1111/dme.12563