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- Title
Lung-specific expression of human mutant p53-273H is associated with a high frequency of lung adenocarcinoma in transgenic mice.
- Authors
Wenrui Duan; Haiming Ding; Subler, Mark A.; Wei-Guo Zhu; Huiming Zhang; Stoner, Gary D.; Windle, Jolene J.; Otterson, Greogory A.; Villalona-Calero, Miguel A.
- Abstract
Investigates the tumorigenic potential of mutant p53 when selectively expressed in lung tissue. Expression of human p53-273H in lungs of transgenic mice; Tumor formation in p53 transgenic mice; Identification of SP-C/p53-273H transgenic mice.
- Subjects
ONCOGENIC viruses; LUNG tumors; TRANSGENIC animals
- Publication
Oncogene, 2002, Vol 21, Issue 51, p7831
- ISSN
0950-9232
- Publication type
Article
- DOI
10.1038/sj.onc.1205909