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Different contributions of chemokine N-terminal features attest to a different ligand binding mode and a bias towards activation of ACKR3/CXCR7 compared with CXCR4 and CXCR3.
Published in:
2018
By:
- Szpakowska, Martyna;
- Nevins, Amanda M.;
- Meyrath, Max;
- Rhainds, David;
- D'huys, Thomas;
- Guité‐Vinet, François;
- Dupuis, Nadine;
- Gauthier, Pierre‐Arnaud;
- Counson, Manuel;
- Kleist, Andrew;
- St‐Onge, Geneviève;
- Hanson, Julien;
- Schols, Dominique;
- Volkman, Brian F.;
- Heveker, Nikolaus;
- Chevigné, Andy;
- D'huys, Thomas;
- Guité-Vinet, François;
- Gauthier, Pierre-Arnaud;
- St-Onge, Geneviève
Publication type:
journal article
Carbohydrate-binding protein from stinging nettle as fusion inhibitor for SARS-CoV-2 variants of concern.
Published in:
Frontiers in Cellular & Infection Microbiology, 2022, v. 12, p. 1, doi. 10.3389/fcimb.2022.989534
By:
- Vanhulle, Emiel;
- D'huys, Thomas;
- Provinciael, Becky;
- Stroobants, Joren;
- Camps, Anita;
- Noppen, Sam;
- Schols, Dominique;
- Van Damme, Els J. M.;
- Maes, Piet;
- Stevaert, Annelies;
- Vermeire, Kurt
Publication type:
Article
The Low-Cost Compound Lignosulfonic Acid (LA) Exhibits Broad-Spectrum Anti-HIV and Anti-HSV Activity and Has Potential for Microbicidal Applications.
Published in:
PLoS ONE, 2015, v. 10, n. 7, p. 1, doi. 10.1371/journal.pone.0131219
By:
- Gordts, Stephanie C.;
- Férir, Geoffrey;
- D’huys, Thomas;
- Petrova, Mariya I.;
- Lebeer, Sarah;
- Snoeck, Robert;
- Andrei, Graciela;
- Schols, Dominique
Publication type:
Article
Aspartate-Based CXCR4 Chemokine Receptor Binding of Cross-Bridged Tetraazamacrocyclic Copper(II) and Zinc(II) Complexes.
Published in:
Chemistry - A European Journal, 2016, v. 22, n. 36, p. 12916, doi. 10.1002/chem.201601468
By:
- Maples, Randall D.;
- Cain, Amy N.;
- Burke, Benjamin P.;
- Silversides, Jon D.;
- Mewis, Ryan E.;
- D'huys, Thomas;
- Schols, Dominique;
- Linder, Douglas P.;
- Archibald, Stephen J.;
- Hubin, Timothy J.
Publication type:
Article
Copper-64 PET imaging of the CXCR4 chemokine receptor using a cross-bridged cyclam bis-tetraazamacrocyclic antagonist.
Published in:
Journal of Nuclear Medicine, 2019, v. 60, n. 12, p. 1, doi. 10.2967/jnumed.118.218008
By:
- Burke, Benjamin P.;
- Miranda, Cecilia S.;
- Lee, Rhiannon E.;
- Renard, Isaline;
- Nigam, Shubhanchi;
- Clemente, Gonҫalo S.;
- D’Huys, Thomas;
- Ruest, Torsten;
- Domarkas, Juozas;
- Thompson, James A.;
- Hubin, Timothy J.;
- Schols, Dominique;
- Cawthorne, Christopher J.;
- Archibald, Stephen J.
Publication type:
Article
Rigid Macrocycle Metal Complexes as CXCR4 Chemokine Receptor Antagonists: Influence of Ring Size.
Published in:
Pharmaceutics, 2024, v. 16, n. 8, p. 1000, doi. 10.3390/pharmaceutics16081000
By:
- Renard, Isaline;
- D'huys, Thomas;
- Burke, Benjamin P.;
- Ajoleza, Trisha;
- Cain, Amy N.;
- Funwie, Neil L.;
- Khan, Abid;
- Maples, Danny L.;
- Maples, Randall D.;
- Matz, Dallas L.;
- McRobbie, Graeme;
- Ullom, Robert;
- Prior, Timothy J.;
- Linder, Douglas P.;
- Van Loy, Tom;
- Hubin, Timothy J.;
- Schols, Dominique;
- Archibald, Stephen J.
Publication type:
Article
Comparison of cell-based assays for the identification and evaluation of competitive CXCR4 inhibitors.
Published in:
PLoS ONE, 2017, v. 12, n. 4, p. 1, doi. 10.1371/journal.pone.0176057
By:
- Van Hout, Anneleen;
- D’huys, Thomas;
- Oeyen, Merel;
- Schols, Dominique;
- Van Loy, Tom
Publication type:
Article

Found: 7

Different contributions of chemokine N-terminal features attest to a different ligand binding mode and a bias towards activation of ACKR3/CXCR7 compared with CXCR4 and CXCR3.

Carbohydrate-binding protein from stinging nettle as fusion inhibitor for SARS-CoV-2 variants of concern.

The Low-Cost Compound Lignosulfonic Acid (LA) Exhibits Broad-Spectrum Anti-HIV and Anti-HSV Activity and Has Potential for Microbicidal Applications.

Aspartate-Based CXCR4 Chemokine Receptor Binding of Cross-Bridged Tetraazamacrocyclic Copper(II) and Zinc(II) Complexes.

Copper-64 PET imaging of the CXCR4 chemokine receptor using a cross-bridged cyclam bis-tetraazamacrocyclic antagonist.

Rigid Macrocycle Metal Complexes as CXCR4 Chemokine Receptor Antagonists: Influence of Ring Size.

Comparison of cell-based assays for the identification and evaluation of competitive CXCR4 inhibitors.