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- Title
Clinical Outcomes of COVID-19 Patients with Type 2 Diabetes: A Population-Based Study in Korea.
- Authors
Ji Hong You; Sang Ah Lee; Sung-Youn Chun; Sun Ok Song; Byung-Wan Lee; Dae Jung Kim; Boyko, Edward J.
- Abstract
Background: The aim of this study was to evaluate clinical outcomes in coronavirus disease 2019 (COVID-19) positive patients with type 2 diabetes compared to those without diabetes in Korea. Methods: We extracted claims data for patients diagnosed with COVID-19 from the National Health Insurance Service database in Korea from January 20, 2020 to March 31, 2020. We followed up this cohort until death from COVID-19 or discharge from hospital. Results: A total of 5,473 patients diagnosed with COVID-19 were analyzed, including 495 with type 2 diabetes and 4,978 without diabetes. Patients with type 2 diabetes were more likely to be treated in the intensive care unit (ICU) (P<0.0001). The incidence of inhospital mortality was higher in patients with type 2 diabetes (P<0.0001). After adjustment for age, sex, insurance status, and comorbidities, odds of ICU admission (adjusted odds ratio [OR], 1.59; 95% confidence interval [CI], 1.02 to 2.49; P=0.0416) and in-hospital mortality (adjusted OR, 1.90; 95% CI, 1.13 to 3.21; P=0.0161) among patients with COVID-19 infection were significantly higher in those with type 2 diabetes. However, there was no significant difference between patients with and without type 2 diabetes in ventilator, oxygen therapy, antibiotics, antiviral drugs, antipyretics, and the incidence of pneumonia after adjustment. Conclusion: COVID-19 positive patients with type 2 diabetes had poorer clinical outcomes with higher risk of ICU admission and in-hospital mortality than those without diabetes. Therefore, medical providers need to consider this more serious clinical course when planning and delivering care to type 2 diabetes patients with COVID-19 infection.
- Subjects
SOUTH Korea; COVID-19; TYPE 2 diabetes; HOSPITAL mortality; NATIONAL health insurance; HOSPITAL admission &; discharge; GREAT Britain. National Health Service
- Publication
Endocrinology & Metabolism, 2020, Vol 35, Issue 4, p901
- ISSN
2093-596X
- Publication type
Article
- DOI
10.3803/EnM.2020.787