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- Title
Overexpression of the paternally expressed gene 10 (PEG10) from the imprinted locus on chromosome 7q21 in high-risk B-cell chronic lymphocytic leukemia.
- Authors
Kainz, Birgit; Shehata, Medhat; Bilban, Martin; Kienle, Dirk; Heintel, Daniel; Krömer-Holzinger, Elisabeth; Le, Trang; Kröber, Alexander; Heller, Gerwin; Schwarzinger, Ilse; Demirtas, Dita; Chott, Andreas; Döhner, Hartmut; Zöchbauer-Müller, Sabine; Fonatsch, Christa; Zielinski, Christoph; Stilgenbauer, Stephan; Gaiger, Alexander; Wagner, Oswald; Jäger, Ulrich
- Abstract
We report high expression of the maternally imprinted gene PEG10 in high-risk B-CLL defined by high LPL mRNA expression. Differential expression was initially identified by microarray analysis and confirmed by real time PCR in 42 B-CLL patients. mRNA expression ranged from 0.3- to 375.4-fold compared to normal peripheral blood mononuclear cells (PBMNC). Expression levels in CD19
- Publication
International Journal of Cancer, 2007, Vol 121, Issue 9, p1984
- ISSN
0020-7136
- Publication type
Article
- DOI
10.1002/ijc.22929