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- Title
Single indurated brown nodulo-plaque in a young male.
- Authors
Taneja, Neha; Khandpur, Sujay; Arava, Sudheer; Vyas, Surabhi
- Abstract
About 10% of patients with RDD have skin lesions, and in 3% of cases, the disease is limited to the skin.[[1]] The features which differentiate cutaneous RDD from systemic RDD include later age of onset (median age, 43.5 years) and a female predominance (2:1) in cutaneous disease.[[2]] RDD has a median age of onset as 20.6 years and is slightly more common in males (1.4:1). Rosai-Dorfman disease (RDD), also known as sinus histiocytosis with massive lymphadenopathy, is a rare, benign, self-limiting non-Langerhans cell histiocytosis of unknown etiology that was first described in 1969 by Rosai and Dorfman. The polyclonal nature of the infiltrate in lesions and the clinical course of spontaneous remission over months to years suggest that cutaneous RDD is a benign reactive process rather than a neoplastic disorder.
- Subjects
SARCOIDOSIS; LYMPHADENITIS; MAGNETIC resonance imaging; SKIN diseases; NON-langerhans-cell histiocytosis; DIAGNOSIS; PROGNOSIS
- Publication
Indian Dermatology Online Journal, 2021, Vol 12, Issue 4, p649
- ISSN
2229-5178
- Publication type
Article
- DOI
10.4103/idoj.IDOJ_464_20