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- Title
Effects of Early Treatment With Statins on Short-term Clinical Outcomes in Acute Coronary Syndromes.
- Authors
Briel, Matthias; Schwartz, Gregory G.; Thompson, Peter L.; de Lemos, James A.; Blazing, Michael A.; van Es, Gerrit-Anne; Kavikcioglu, Meral; Arntz, Hans-Richard; den Hartog, Frank R.; Veeger, J. G. M.; Colivicchi, Furio; Dupuis, Jocelyn; Okazaki, Shinya; Wright, Scott; Bucher, Heiner C.; Nordmann, Alain J.
- Abstract
This article attempts to evaluate relevant outcomes of patients from randomized controlled trials comparing early statin therapy with placebo or usual care at one and four months following acute coronary syndromes (ACS). The short-term impact of early treatment with statins in patients after the onset of ACS for the outcomes of death, myocardial infarction, and stroke is unknown. The authors concluded that, based on the available evidence, initiation of statin therapy within 14 days following onset of ACS does not reduce death, myocardial infarction, or stroke up to four months.
- Subjects
STATINS (Cardiovascular agents); CLINICAL trials; MYOCARDIAL infarction; CEREBROVASCULAR disease; DEATH; PLACEBOS
- Publication
JAMA: Journal of the American Medical Association, 2006, Vol 295, Issue 17, p2046
- ISSN
0098-7484
- Publication type
Article
- DOI
10.1001/jama.295.17.2046