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Development of a Stable Respiratory Syncytial Virus Pre-Fusion Protein Powder Suitable for a Core-Shell Implant with a Delayed Release in Mice: A Proof of Concept Study.
Published in:
Pharmaceutics, 2019, v. 11, n. 10, p. 510, doi. 10.3390/pharmaceutics11100510
By:
- Beugeling, Max;
- Amssoms, Katie;
- Cox, Freek;
- De Clerck, Ben;
- Van Gulck, Ellen;
- Verwoerd, Jeroen A.;
- Kraus, Guenter;
- Roymans, Dirk;
- Baert, Lieven;
- Frijlink, Henderik W.;
- Hinrichs, Wouter L. J.
Publication type:
Article
Design and Preclinical Evaluation of a Nanoparticle Vaccine against Respiratory Syncytial Virus Based on the Attachment Protein G.
Published in:
Vaccines, 2024, v. 12, n. 3, p. 294, doi. 10.3390/vaccines12030294
By:
- Voorzaat, Richard;
- Cox, Freek;
- van Overveld, Daan;
- Le, Lam;
- Tettero, Lisanne;
- Vaneman, Joost;
- Bakkers, Mark J. G.;
- Langedijk, Johannes P. M.
Publication type:
Article
RSV A2-Based Prefusion F Vaccine Candidates Induce RSV A and RSV B Cross Binding and Neutralizing Antibodies and Provide Protection against RSV A and RSV B Challenge in Preclinical Models.
Published in:
Vaccines, 2023, v. 11, n. 3, p. 672, doi. 10.3390/vaccines11030672
By:
- Cox, Freek;
- Saeland, Eirikur;
- Thoma, Anne;
- van den Hoogen, Ward;
- Tettero, Lisanne;
- Drijver, Joke;
- Vaneman, Cornelis;
- van Polanen, Yolinda;
- Ritschel, Tina;
- Bastian, Arangassery Rosemary;
- Callendret, Benoit;
- Zahn, Roland;
- van der Fits, Leslie
Publication type:
Article
Matrix-M Adjuvated Seasonal Virosomal Influenza Vaccine Induces Partial Protection in Mice and Ferrets against Avian H5 and H7 Challenge.
Published in:
PLoS ONE, 2015, v. 10, n. 9, p. 1, doi. 10.1371/journal.pone.0135723
By:
- Cox, Freek;
- Roos, Anna;
- Hafkemeijer, Nicole;
- Baart, Matthijs;
- Tolboom, Jeroen;
- Dekking, Liesbeth;
- Stittelaar, Koert;
- Goudsmit, Jaap;
- Radošević, Katarina;
- Saeland, Eirikur
Publication type:
Article
Heterosubtypic Neutralizing Monoclonal Antibodies Cross-Protective against H5N1 and H1N1 Recovered from Human IgM<sup>+</sup> Memory B Cells.
Published in:
PLoS ONE, 2008, v. 3, n. 12, p. 1, doi. 10.1371/journal.pone.0003942
By:
- Throsby, Mark;
- van den Brink, Edward;
- Jongeneelen, Mandy;
- Poon, Leo L. M.;
- Alard, Philippe;
- Cornelissen, Lisette;
- Bakker, Arjen;
- Cox, Freek;
- van Deventer, Els;
- Guan, Yi;
- Cinatl, Jindrich;
- ter Meulen, Jan;
- Lasters, Ignace;
- Carsetti, Rita;
- Peiris, Malik;
- de Kruif, John;
- Goudsmit, Jaap
Publication type:
Article
A Double-Blind, Randomized, Placebo-Controlled Phase 1 Study of Ad26.ZIKV.001, an Ad26-Vectored Anti-Zika Virus Vaccine.
Published in:
2021
By:
- Salisch, Nadine C.;
- Stephenson, Kathryn E.;
- Williams, Kristi;
- Cox, Freek;
- van der Fits, Leslie;
- Heerwegh, Dirk;
- Truyers, Carla;
- Habets, Marrit N.;
- Kanjilal, Diane G.;
- Larocca, Rafael A.;
- Abbink, Peter;
- Liu, Jinyan;
- Peter, Lauren;
- Fierro, Carlos;
- De La Barrera, Rafael A.;
- Modjarrad, Kayvon;
- Zahn, Roland C.;
- Hendriks, Jenny;
- Cahill, Conor P.;
- Leyssen, Maarten
Publication type:
journal article
Matrix-M™ adjuvation broadens protection induced by seasonal trivalent virosomal influenza vaccine.
Published in:
Virology Journal, 2015, v. 12, n. 1, p. 1, doi. 10.1186/s12985-015-0435-9
By:
- Cox, Freek;
- Saeland, Eirikur;
- Baart, Matthijs;
- Koldijk, Martin;
- Tolboom, Jeroen;
- Dekking, Liesbeth;
- Koudstaal, Wouter;
- Bengtsson, Karin Lövgren;
- Goudsmit, Jaap;
- Radošević, Katarina
Publication type:
Article
Ad26.M.Env ZIKV vaccine protects pregnant rhesus macaques and fetuses against Zika virus infection.
Published in:
NPJ Vaccines, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41541-024-00927-8
By:
- Martinot, Amanda J.;
- Cox, Freek;
- Abbink, Peter;
- Hecht, Jonathan L.;
- Bronson, Roderick;
- Borducchi, Erica N.;
- Rinaldi, William J.;
- Ferguson, Melissa J.;
- De La Barrera, Rafael A.;
- Zahn, Roland;
- van der Fits, Leslie;
- Barouch, Dan H.
Publication type:
Article
Combination Ad26.RSV.preF/preF protein vaccine induces superior protective immunity compared with individual vaccine components in preclinical models.
Published in:
NPJ Vaccines, 2023, v. 8, n. 1, p. 1, doi. 10.1038/s41541-023-00637-7
By:
- Saeland, Eirikur;
- van der Fits, Leslie;
- Bolder, Renske;
- Heemskerk-van der Meer, Marjolein;
- Drijver, Joke;
- van Polanen, Yolinda;
- Vaneman, Cornelis;
- Tettero, Lisanne;
- Cox, Freek;
- Serroyen, Jan;
- Jorgensen, Matthew J.;
- Langedijk, Johannes P. M.;
- Schuitemaker, Hanneke;
- Callendret, Benoit;
- Zahn, Roland C.
Publication type:
Article
A novel helper phage that improves phage display selection efficiency by preventing the amplification of phages without recombinant protein.
Published in:
Nucleic Acids Research, 2003, v. 31, n. 11, p. e59, doi. 10.1093/nar/gng058
By:
- Kramer, R. Arjen;
- Cox, Freek;
- van der Horst, Marieke;
- van den Oudenrijn, Sonja;
- Res, Pieter C. M.;
- Bia, Judith;
- Logtenberg, Ton;
- de Kruif, John
Publication type:
Article
HA Antibody-Mediated FcγRIIIa Activity Is Both Dependent on FcR Engagement and Interactions between HA and Sialic Acids.
Published in:
Frontiers in Immunology, 2016, p. 1, doi. 10.3389/fimmu.2016.00399
By:
- Cox, Freek;
- Kwaks, Ted;
- Brandenburg, Boerries;
- Koldijk, Martin H.;
- Klaren, Vincent;
- Smal, Bastiaan;
- Korse, Hans J. W. M.;
- Geelen, Eric;
- Tettero, Lisanne;
- Zuijdgeest, David;
- Stoop, Esther J. M.;
- Saeland, Eirikur;
- Vogels, Ronald;
- Friesen, Robert H. E.;
- Koudstaal, Wouter;
- Goudsmit, Jaap;
- Borrego, Francisco;
- Bin Su
Publication type:
Article
Protection against H5N1 Influenza Virus Induced by Matrix-M Adjuvanted Seasonal Virosomal Vaccine in Mice Requires Both Antibodies and T Cells.
Published in:
PLoS ONE, 2015, v. 10, n. 12, p. 1, doi. 10.1371/journal.pone.0145243
By:
- Cox, Freek;
- Baart, Matthijs;
- Huizingh, Jeroen;
- Tolboom, Jeroen;
- Dekking, Liesbeth;
- Goudsmit, Jaap;
- Saeland, Eirikur;
- Radošević, Katarina
Publication type:
Article
Universal paramyxovirus vaccine design by stabilizing regions involved in structural transformation of the fusion protein.
Published in:
Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-48059-w
By:
- Langedijk, Johannes P. M.;
- Cox, Freek;
- Johnson, Nicole V.;
- van Overveld, Daan;
- Le, Lam;
- van den Hoogen, Ward;
- Voorzaat, Richard;
- Zahn, Roland;
- van der Fits, Leslie;
- Juraszek, Jarek;
- McLellan, Jason S.;
- Bakkers, Mark J. G.
Publication type:
Article
Adenoviral vector type 26 encoding Zika virus (ZIKV) M-Env antigen induces humoral and cellular immune responses and protects mice and nonhuman primates against ZIKV challenge.
Published in:
PLoS ONE, 2018, v. 13, n. 8, p. 1, doi. 10.1371/journal.pone.0202820
By:
- Cox, Freek;
- van der Fits, Leslie;
- Abbink, Peter;
- Larocca, Rafael A.;
- van Huizen, Ella;
- Saeland, Eirikur;
- Verhagen, Janneke;
- Peterson, Rebecca;
- Tolboom, Jeroen;
- Kaufmann, Baerbel;
- Schuitemaker, Hanneke;
- Barouch, Dan H.;
- Zahn, Roland
Publication type:
Article
Human monoclonal antibody combination against SARS coronavirus: synergy and coverage of escape mutants.
Published in:
2006
By:
- Ter Meulen, Jan;
- Van den Brink, Edward N.;
- Poon, Leo L. M.;
- Marissen, Wilfred E.;
- Leung, Cynthia S. W.;
- Cox, Freek;
- Cheung, Chung Y.;
- Bakker, Arjen Q.;
- Bogaards, Johannes A.;
- Van Deventer, Els;
- Preiser, Wolfgang;
- Doerr, Hans Wilhelm;
- Chow, Vincent T.;
- De Kruif, John;
- Peiris, Joseph S. M.;
- Goudsmit, Jaap
Publication type:
journal article

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