We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
The Vietnamese pig as a translational animal model to evaluate tissue engineered heart valves: promising early experience.
- Authors
Gallo, Michele; Poser, Helen; Bottio, Tommaso; Bonetti, Antonella; Franci, Paolo; Naso, Filippo; Buratto, Edward; Zanella, Fabio; Perona, Giovanni; Dal Lin, Carlo; Bianco, Roberto; Spina, Michele; Busetto, Roberto; Marchini, Maurizio; Ortolani, Fulvia; Iop, Laura; Gerosa, Gino; Bottio, Tomaso
- Abstract
Several animal models are currently used for the surgical implantation of either biologic or biopolymeric scaffolds in order to provide in vivo assessment of tissue-engineered heart valves. The Vietnamese pig (VP) is herein proposed as a suitable recipient to test the function of novel bioengineered valve substitutes, in the reconstruction of the right ventricular outflow tract (RVOT). This review aims to provide a complete and exhaustive panel of physiological parameters and methodological information for preclinical studies of tissue-engineered heart valves in the VP animal model.
- Subjects
AORTIC valve surgery; ANIMAL experimentation; BIOLOGICAL models; ECHOCARDIOGRAPHY; GUIDED tissue regeneration; PROSTHETIC heart valves; HOMOGRAFTS; PROSTHETICS; SWINE; TISSUE engineering
- Publication
International Journal of Artificial Organs, 2017, Vol 40, Issue 4, p142
- ISSN
0391-3988
- Publication type
journal article
- DOI
10.5301/ijao.5000568