We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Comparison of the Vaginal Microbiota in Postmenopausal Black and White Women.
- Authors
Hudson, Patricia L; Ling, Wodan; Wu, Michael C; Hayward, Matthew R; Mitchell, Alissa J; Larson, Joseph; Guthrie, Katherine A; Reed, Susan D; Kwon, Douglas S; Mitchell, Caroline M
- Abstract
<bold>Background: </bold>We compared vaginal microbial communities in postmenopausal black and white women.<bold>Methods: </bold>Shotgun sequencing of vaginal swabs from postmenopausal women self-identified as black or white was compared using MiRKAT.<bold>Results: </bold>Vaginal community dominance by Lactobacillus crispatus or Lactobacillusgasseri was more common in 44 postmenopausal black women (n = 12, 27%) than among 44 matched white women (n = 2, 5%; P = .01). No individual taxa were significantly more abundant in either group.<bold>Conclusions: </bold>We identified small overall differences in vaginal microbial communities of black and white postmenopausal women. L. crispatus dominance was more common in black women.<bold>Clinical Trials Registration: </bold>NCT02516202 (MsFLASH05) and NCT01418209 (MsFLASH03).
- Subjects
WHITE women; BLACK women; HUMAN microbiota; CLINICAL trial registries; SHOTGUN sequencing
- Publication
Journal of Infectious Diseases, 2021, Vol 224, Issue 11, p1945
- ISSN
0022-1899
- Publication type
journal article
- DOI
10.1093/infdis/jiaa780