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- Title
Colorectal cancer presenting as bone metastasis.
- Authors
Babu, M. C. Suresh; Garg, Sunny; Lakshmaiah, K. C.; Babu, K. Govind; Kumar, Rekha V.; Loknatha, D.; Abraham, Linu Jacob; Rajeev, L. K.; Lokesh, K. N.; Rudresha, A. H.; Rao, Suparna Ajit; Suresh Babu, M C
- Abstract
<bold>Introduction: </bold>Bone metastasis is a rare site of metastasis, seen in only 3.7-11% of clinical cases. Isolated bone involvement has been reported very rarely in literature. Moreover, the patients who have bone metastasis at presentation are even rare.<bold>Objectives: </bold>To discuss the demographic characteristics, carcinoembryonic antigen (CEA) levels, pattern of bone involvement, and their correlation with survival in patients of colorectal cancer that have bone metastasis at the time of presentation.<bold>Materials and Methods: </bold>Retrospectively, tumor registry was analyzed for the cases of colorectal cancer presenting with bone metastasis between 2008 and 2013. Survival curves were generated by Kaplan-Meier method and analyzed using the log-rank test.<bold>Results: </bold>Ten such patients were identified (male:female = 7:3) of the total 410 patients. Median age was 41 years (22-50 years). All patients were Conclusions: In this study, the patients of colorectal cancer presenting with bone metastasis were of male sex and younger age. The factors that were associated with reduced survival were extraosseous and liver involvement.
- Subjects
COLON cancer; CARCINOEMBRYONIC antigen; TUMORS; CANCER chemotherapy; METASTASIS; AGE distribution; BONE tumors; COLON tumors; HUMAN reproduction; PROGNOSIS; RECTUM tumors; TUMOR antigens; KAPLAN-Meier estimator
- Publication
Journal of Cancer Research & Therapeutics, 2017, Vol 13, Issue 1, p80
- ISSN
0973-1482
- Publication type
journal article
- DOI
10.4103/0973-1482.181177