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- Title
Convenient Synthesis of Functionalized Bis-ureidopyrimidinones Based on Thiol-yne Reaction.
- Authors
Peng, Hui ‐ Qing; Sun, Cai ‐ Li; Xu, Jiang ‐ Fei; Niu, Li ‐ Ya; Chen, Yu ‐ Zhe; Wu, Li ‐ Zhu; Tung, Chen ‐ Ho; Yang, Qing ‐ Zheng
- Abstract
The preparation of functionalized bis-ureidopyrimidinones ( Bis-UPy) through the thiol-yne reaction is described. Various Bis-UPys with different functional groups were synthesized by using the readily available functionalized alkynes and UPy-thiol to affirm the simplicity and versatility of the methodology.
- Subjects
FUNCTIONAL groups; ALKYNES; NUCLEOPHILIC reactions; DISULFIDES; THIOLS; COLUMN chromatography; AMINO group
- Publication
Chemistry - A European Journal, 2014, Vol 20, Issue 37, p11699
- ISSN
0947-6539
- Publication type
Article
- DOI
10.1002/chem.201402955