We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Inhibitory neurotransmitter serotonin and excitatory neurotransmitter dopamine both decrease food intake in Chinese perch (<italic>Siniperca chuatsi</italic>).
- Authors
He, Yu-Hui; Li, Ling; Liang, Xu-Fang; He, Shan; Zhao, Luo; Zhang, Yan-Peng
- Abstract
Aminergic neurotransmitters play important roles in the regulation of food intake. However, their effects on feeding in fish have been less explored and still unclear. In the present study, the effects of serotonin (5-HT) and dopamine (DA) on food intake were evaluated through intraventricular (ICV) administration in Chinese perch (<italic>Siniperca chuatsi</italic>) and the mRNA expression levels of neuropeptide Y (<italic>NPY</italic>), agouti gene-related protein (<italic>AgRP</italic>), and pro-opiomelanocortin (<italic>POMC</italic>) were detected. At 1 h post-injection, 5-HT significantly decreased food intake in a dose-dependent manner. The mRNA expression of <italic>NPY</italic> and <italic>AgRP</italic> were significantly decreased (<italic>p</italic> < 0.05), whereas the mRNA expression of <italic>POMC</italic> was significantly increased (<italic>p</italic> < 0.05), suggesting the involvement of <italic>NPY</italic>, <italic>AgRP</italic>, and <italic>POMC</italic> in inhibitory action of 5-HT on food intake in Chinese perch. DA significantly decreased (<italic>p</italic> < 0.05) food intake and <italic>AgRP</italic> mRNA expression at 1 h post-injection, indicating the inhibitory effect of DA on food intake might be mediated through <italic>AgRP</italic>. This might shed new light on the regulation of food intake in Chinese perch.
- Publication
Fish Physiology & Biochemistry, 2018, Vol 44, Issue 1, p175
- ISSN
0920-1742
- Publication type
Article
- DOI
10.1007/s10695-017-0422-8