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- Title
Isolation and Bioassay of a New Terminalone A from Terminalia arjuna.
- Authors
Bushra; Rehman, Khalil ur; Khan, Dilfaraz; Almehizia, Abdulrahman A.; Naglah, Ahmed M.; Al-Wasidi, Asma S.; Refat, Moamen S.; El-Sayed, Mohamed Y.; Ullah, Hamid; Khan, Shafiullah
- Abstract
Terminalia arjuna possesses significant cardioprotective, antidiabetic and antioxidant properties as these properties are described in Ayurveda. In the present study, three flavonoids were isolated through the separation and chromatographic purification of the whole plant material of T. arjuna. Spectroscopic characterization identified one of them as a new flavonoid "Terminalone A (1)" and two known flavonoids i.e., 6-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-chromen-4-one (2) and 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one (3). The bioactivity studies showed considerable antibacterial and antioxidant (DPPH radical scavenging) potential for all the three compounds 1–3 where the compound 1 showed strong antibacterial and antioxidant activity.
- Subjects
TERMINALIA arjuna; BIOLOGICAL assay; ANTIBACTERIAL agents; REACTIVE oxygen species; AYURVEDIC medicine; FLAVONOIDS; FREE radicals
- Publication
Molecules, 2023, Vol 28, Issue 3, p1015
- ISSN
1420-3049
- Publication type
Article
- DOI
10.3390/molecules28031015