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- Title
Six New Phragmalin Limonoids from the Stems of Chukrasia tabularis A. Juss.
- Authors
Wang, Yan-Cui; Kong, Fan-Dong; Wang, Hao; Mei, Wen-Li; Liu, Shou-Bai; Zhao, You-Xing; Dai, Hao-Fu; Epifano, Francesco
- Abstract
Six new phragmalin limonoids, named moluccensin Z1 (1), moluccensin Z2 (2), carapanolide Y (3), tabulalin N (4), chukvelutilide A1 (5), and velutinasin J (6), as well as two known compounds, chukvelutilide A (7) and velutinasin D (8) were isolated from the stems of Chukrasia tabularis A. Juss. The structures of the new compounds 1–6 were confirmed by spectroscopic methods, including IR and HRESIMS, as well as 1D and 2D NMR, and by comparisons with the data of known analogues. All compounds were tested for α-glucosidase and acetylcholinesterase inhibitory activities. However, none of the compounds was active against α-glucosidase and acetylcholinesterase in vitro.
- Subjects
LIMONOIDS; GLUCOSIDASES; GLYCOSIDASES; CHEMICAL reactions; CATALYSTS
- Publication
Molecules, 2018, Vol 23, Issue 11, p3024
- ISSN
1420-3049
- Publication type
Article
- DOI
10.3390/molecules23113024