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- Title
Effect of Highly Mineralized Natural Water on Redox Processes in HaCaT Keratinocytes.
- Authors
Zaitseva, N.; Chechushkov, A.; Kozhin, P.; Lemza, A.; Tkachev, V.; Solomatina, M.; Starostenko, V.
- Abstract
We studied ROS production by HaCaT keratinocytes, the state of transmembrane mitochondrial potential, and activation of transcription factor Nrf2 in response to brine exposure. It was demonstrated that this exposure induces rapid but moderate decrease in mitochondrial potential, stimulates ROS production, and leads to activation of transcription factor Nrf2.
- Subjects
KERATINOCYTES; TRANSCRIPTION factors; CELLULAR signal transduction; MINERAL waters; OXIDATION-reduction reaction
- Publication
Bulletin of Experimental Biology & Medicine, 2014, Vol 156, Issue 6, p810
- ISSN
0007-4888
- Publication type
Article
- DOI
10.1007/s10517-014-2457-5