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- Title
Association of Euterpe oleracea , Bixa orellana , Myciaria dubia , and Astrocaryum aculeatum (the Terasen ® Nutraceutical) Increases the Lifespan of Caenorhabditis elegans.
- Authors
de Melo, Ester Lopes; Tavares, Bruno Augusto Machado; Colares, Nayara Nílcia Dias; do Nascimento, Aline Lopes; Carvalho, Helison de Oliveira; Castro, Andrés Navarrete; Pereira, Arlindo César Matias; Winter, Carlos Eduardo; Sena, Iracirema da Silva; Moreira, Luiz Fernando; Carvalho, José Carlos Tavares
- Abstract
Aging is a complex process associated with tissue degeneration and an increased risk of age-related diseases. This study aimed to evaluate the impact of Terasen®, a nutraceutical containing standardized extracts of Euterpe oleracea, Myrciaria dubia, and purified oil of Bixa orellana and Astrocaryum aculeatum on the lifespan of Caenorhabditis elegans. The findings demonstrated that Terasen® exhibited significant radical scavenging in vitro, decreased the feeding behavior of C. elegans without affecting the animals' final size, increased the eggs laid in a concentration-dependent fashion, although the total progeny was reduced compared to the control, and increased the median and maximum lifespan. These findings suggest that Terasen® may improve the lifespan in C. elegans, warranting further investigation.
- Subjects
FUNCTIONAL foods; IN vitro studies; HUMAN reproduction; HUMAN growth; FOOD habits; MEDICINAL plants; NEMATODES; CAENORHABDITIS elegans; VEGETABLE oils; ANIMAL experimentation; HUMAN locomotion; EUTERPE; AGING; RESEARCH funding; LONGEVITY; PLANT extracts; FREE radical scavengers
- Publication
Journal of Ageing & Longevity, 2023, Vol 3, Issue 4, p494
- ISSN
2673-9259
- Publication type
Article
- DOI
10.3390/jal3040022