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- Title
Predictive role of laboratory markers and clinical features for recurrent Henoch-Sch€onlein Purpura in childhood: A study from Turkey.
- Authors
Gökçe, Şule; Kurugöl, Zafer; Koturoğlu, Güldane; Aslan, Aslı
- Abstract
Objectives: Henoch Schönlein Purpura is the most common systemic vasculitis of the childhood. The objective of this study was to evaluate whether there is a clinical significance of laboratory parameters and clinical features on the prediction of the recurrent Henoch Schönlein Purpura in children.Methods: For recurrent Henoch Schönlein Purpura, several laboratory results and clinical features were examined to identify the predictor factors via the logistic regression model in 99 children with Henoch Schönlein Purpura. A p-value of <.05 was considered significant. The patients were divided into two groups as the first attack and the recurrent.Results: The demographic features and laboratory results were not found statistically significant between the two groups (p > .05). The multiple logistic regression model showed that the risk of recurrent Henoch Schönlein Purpura increased 17.2-fold in children with Henoch Schönlein Purpura affected by the four systems including skin, joint, kidney and gastrointestinal system [Odds Ratio (OR) 17.2, 95% CI 1.4-12; p < .001].Conclusion: In our inpatient population, the laboratory characteristics were detected not to be a factor for the prediction of recurrence. However, the four systems including skin, joint, kidney and gastrointestinal involvement may be used as a predictive factor for recurrent HSP.
- Subjects
SCHOENLEIN-Henoch purpura; VASCULITIS; CHILDREN; DISEASE relapse; PURPURA (Pathology)
- Publication
Modern Rheumatology, 2020, Vol 30, Issue 6, p1047
- ISSN
1439-7595
- Publication type
Article
- DOI
10.1080/14397595.2019.1690966