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- Title
Early diagnosis and treatment for remission of clinically amyopathic dermatomyositis complicated by rapid progress interstitial lung disease: a report of two cases.
- Authors
Horai, Yoshiro; Isomoto, Eriko; Koga, Tomohiro; Okada, Akitomo; Kawashiri, Shin-ya; Tamai, Mami; Yamasaki, Satoshi; Nakamura, Hideki; Origuchi, Tomoki; Hamaguchi, Yasuhito; Fujimoto, Manabu; Kuwana, Masataka; Kawakami, Atsushi
- Abstract
We report two cases of clinically amyopathic dermatomyositis (CADM) complicated by rapid progress interstitial lung disease (RPILD). The diagnosis of CADM was based on Gottron's papule and RPILD, and the absence of muscle weakness. The female patients were treated with early immunosuppressive therapies including steroid pulse therapy, resulting in significant improvement in respiratory symptoms, clinical data, and imaging. Measurement of anti-CADM-140/MDA5 antibody was useful for obtaining a definitive diagnosis of CADM in these cases.
- Subjects
EARLY diagnosis; DISEASE remission; DERMATOMYOSITIS; MUSCLE weakness; INTERSTITIAL lung diseases; IMMUNOSUPPRESSIVE agents; SYMPTOMS; THERAPEUTICS
- Publication
Modern Rheumatology, 2013, Vol 23, Issue 1, p190
- ISSN
1439-7595
- Publication type
Article
- DOI
10.3109/s10165-012-0637-6