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- Title
What Is the Evidence Supporting Osteobiologic Use in Revision Anterior Cervical Discectomy and Fusion?
- Authors
Muthu, Sathish; Diniz, Sara Elisa; Viswanathan, Vibhu Krishnan; Hsieh, Patrick C.; Abedi, Aidin; Yoon, Tim; Meisel, Hans Jörg; Buser, Zorica; Rodrigues-Pinto, Ricardo; Knowledge Forum Degenerative, AO Spine
- Abstract
Study design: Systematic literature review Objective: To analyze the literature and describe the evidence supporting osteobiologic use in revision anterior cervical discectomy and fusion (ACDF) surgery. Methods: A systematic search of PubMed/MEDLINE, EMBASE, Cochrane library, and ClinicalTrials.gov databases was conducted for literature reporting the use of osteobiologics in revision ACDF. We searched for studies reporting outcomes of using any osteobiologic use in revision ACDF surgeries (independently of the number of levels) in the above databases. Results: There are currently no studies in the literature describing the outcome and comparative efficacy of diverse osteobiologic agents in the context of revision ACDF surgery. A majority of the current evidence is based only upon studies involving primary ACDF surgery. Conclusion: The current study highlights the paucity of literature evidence on the role of diverse osteobiologics in revision ACDF, and foregrounds the need for high-quality evidence on this subject.
- Subjects
REOPERATION; DISCECTOMY; LONGITUDINAL ligaments; EXPERIMENTAL design
- Publication
Global Spine Journal, 2024, Vol 14, p173S
- ISSN
2192-5682
- Publication type
Article
- DOI
10.1177/21925682221133751