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- Title
Sequence Analysis of Toxin Gene-Bearing Corynebacterium diphtheriae Strains, Australia.
- Authors
Doyle, Christine J.; Mazins, Adam; Graham, Rikki M. A.; Ning-Xia Fang; Smith, Helen V.; Jennison, Amy V.; Fang, Ning-Xia
- Abstract
By conducting a molecular characterization of Corynebacterium diphtheriae strains in Australia, we identified novel sequences, nonfunctional toxin genes, and 5 recent cases of toxigenic cutaneous diphtheria. These findings highlight the importance of extrapharyngeal infections for toxin gene-bearing (functional or not) and non-toxin gene-bearing C. diphtheriae strains. Continued surveillance is recommended.
- Subjects
AUSTRALIA; CORYNEBACTERIUM diphtheriae; CORYNEBACTERIUM; BREVIBACTERIUM; SEQUENCE analysis; DNA mutational analysis; SKIN microbiology; BACTERIAL toxins; COMPARATIVE studies; DIPHTHERIA; DIPHTHERIA vaccines; EPIDEMIOLOGY; GENES; GRAM-positive bacteria; IMMUNIZATION; LEG; RESEARCH methodology; MEDICAL cooperation; MEDICAL protocols; GENETIC mutation; PHARYNX; RESEARCH; RESEARCH funding; SKIN; EVALUATION research; DRUG administration; DRUG dosage; PREVENTION
- Publication
Emerging Infectious Diseases, 2017, Vol 23, Issue 1, p105
- ISSN
1080-6040
- Publication type
journal article
- DOI
10.3201/eid2301.160584