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Circulating Proteomic Signatures of Chronological Age.
Published in:
2015
By:
- Menni, Cristina;
- Kiddle, Steven J;
- Mangino, Massimo;
- Viñuela, Ana;
- Psatha, Maria;
- Steves, Claire;
- Sattlecker, Martina;
- Buil, Alfonso;
- Newhouse, Stephen;
- Nelson, Sally;
- Williams, Stephen;
- Voyle, Nicola;
- Soininen, Hilkka;
- Kloszewska, Iwona;
- Mecocci, Patrizia;
- Tsolaki, Magda;
- Vellas, Bruno;
- Lovestone, Simon;
- Spector, Tim D;
- Dobson, Richard
Publication type:
journal article
Genome‐wide association study of rate of cognitive decline in Alzheimer's disease patients identifies novel genes and pathways.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 8, p. 1134, doi. 10.1002/alz.12106
By:
- Sherva, Richard;
- Gross, Alden;
- Mukherjee, Shubhabrata;
- Koesterer, Ryan;
- Amouyel, Philippe;
- Bellenguez, Celine;
- Dufouil, Carole;
- Bennett, David A.;
- Chibnik, Lori;
- Cruchaga, Carlos;
- del‐Aguila, Jorge;
- Farrer, Lindsay A.;
- Mayeux, Richard;
- Munsie, Leanne;
- Winslow, Ashley;
- Newhouse, Stephen;
- Saykin, Andrew J.;
- Kauwe, John S.K.;
- Crane, Paul K.;
- Green, Robert C.
Publication type:
Article
DEMENTIA SEVERITY AND PROGRESSION: IDENTIFYING PATIENTS AT RISK FOR FASTER COGNITIVE DECLINE.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P926, doi. 10.1016/j.jalz.2017.07.362
By:
- Baker, Elizabeth;
- Iqbal, Ehtesham;
- Johnston, Caroline;
- Broadbent, Matthew;
- Shetty, Hitesch;
- Stewart, Robert;
- Howard, Robert J.;
- Newhouse, Stephen J.;
- Khondoker, Mizan;
- Kiddle, Steven John;
- Dobson, Richard J.B.
Publication type:
Article
ASSESSING TREM2 FUNCTION IN ALZHEIMER’S DISEASE WITH RNA-SEQ.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P590, doi. 10.1016/j.jalz.2017.07.221
By:
- Carbajosa, Guillermo;
- Wang, Hong;
- Ryder, John;
- Lawless, Nathan;
- Hodges, Angela;
- Collier, David A.;
- O'Neill, Michael J.;
- Dobson, Richard J.B.;
- Newhouse, Stephen J.
Publication type:
Article
ASSESSING TREM2 RISK VARIANTS IN ALZHEIMER'S DISEASE WITH RNA-SEQ.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P452, doi. 10.1016/j.jalz.2016.06.875
By:
- Carbajosa, Guillermo;
- Wang, Hong;
- Ryder, John;
- Collier, David A.;
- O'Neill, Michael J.;
- Dobson, Richard JB.;
- Newhouse, Stephen J.
Publication type:
Article
ELECTRONIC RECORDS FOR DEMENTIA RESEARCH: DO BEHAVIOURAL DISTURBANCES, ANTIHYPERTENSIVES AND ANTIDEPRESSANTS INFLUENCE DECLINE TRAJECTORIES?
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P1056, doi. 10.1016/j.jalz.2016.06.2206
By:
- Baker, Elizabeth;
- Iqbal, Ehtesham;
- Broadbent, Matthew;
- Stewart, Robert;
- Khondoker, Mizanur;
- Newhouse, Stephen J.;
- Dobson, Richard J.B.
Publication type:
Article
ASSESSMENT OF AN ALZHEIMER’S GENE EXPRESSION SIGNATURE.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P415, doi. 10.1016/j.jalz.2016.06.786
By:
- Patel, Hamel;
- Sattlecker, Martina;
- Leirer, Daniel;
- di Forti, Marta;
- Mondelii, Valeria;
- Murray, Robin M.;
- Dobson, Richard J.B.;
- Newhouse, Stephen J.
Publication type:
Article
Genetic influences on metabolite levels in Alzheimer’s disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P279, doi. 10.1016/j.jalz.2015.07.373
By:
- Proitsi, Petroula;
- Min, Kim;
- Whiley, Luke;
- Newhouse, Stephen;
- Johnston, Caroline;
- Soininen, Hilkka;
- Kloszewska, Iwona;
- Mecocci, Patrizia;
- Tsolaki, Magda;
- Vellas, Bruno;
- Sham, Pak;
- Lovestone, Simon;
- Powell, John F.;
- Quigley, Cristina Legido;
- Dobson, Richard J.B.
Publication type:
Article
Alzheimer's disease biomarker discovery using SOMAscan multiplexed protein technology.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2014, v. 10, n. 6, p. 724, doi. 10.1016/j.jalz.2013.09.016
By:
- Sattlecker, Martina;
- Kiddle, Steven J.;
- Newhouse, Stephen;
- Proitsi, Petroula;
- Nelson, Sally;
- Williams, Stephen;
- Johnston, Caroline;
- Killick, Richard;
- Simmons, Andrew;
- Westman, Eric;
- Hodges, Angela;
- Soininen, Hilkka;
- Kłoszewska, Iwona;
- Mecocci, Patrizia;
- Tsolaki, Magda;
- Vellas, Bruno;
- Lovestone, Simon;
- Dobson, Richard J.B.
Publication type:
Article
Genome-wide association analysis identifies common variants associated with measures of disease progression in patients with Alzheimer's disease
Published in:
2012
By:
- Newhouse, Stephen;
- Proitsi, Petroula;
- Sattlecker, Martina;
- Lunnon, Katie;
- Ibrahim, Zina;
- Johnston, Caroline;
- Lourdusamy, Anbarasu;
- Lupton, Michelle;
- Powell, John;
- Khondoker, Mizanur;
- Soininen, Hilkka;
- Kloszewska, Iwona;
- Mecocci, Patrizia;
- Tsolaki, Magda;
- Vellas, Bruno;
- Lovestone, Simon;
- Hodges, Angela;
- Dobson, Richard
Publication type:
Abstract
Microarray, qPCR, and KCNJ5 sequencing of aldosterone-producing adenomas reveal differences in genotype and phenotype between zona glomerulosa- and zona fasciculata-like tumors.
Published in:
2012
By:
- Azizan EA;
- Lam BY;
- Newhouse SJ;
- Zhou J;
- Kuc RE;
- Clarke J;
- Happerfield L;
- Marker A;
- Hoffman GJ;
- Brown MJ;
- Azizan, Elena A B;
- Lam, Brian Y H;
- Newhouse, Stephen J;
- Zhou, Junhua;
- Kuc, Rhoda E;
- Clarke, Jennifer;
- Happerfield, Lisa;
- Marker, Alison;
- Hoffman, Gary J;
- Brown, Morris J
Publication type:
journal article
Brain Transcriptome Sequencing of a Natural Model of Alzheimer's Disease.
Published in:
Frontiers in Aging Neuroscience, 2017, v. 9, p. 1, doi. 10.3389/fnagi.2017.00064
By:
- Altimiras, Francisco;
- Uszczynska-Ratajczak, Barbara;
- Camara, Francisco;
- Vlasova, Anna;
- Palumbo, Emilio;
- Newhouse, Stephen;
- Deacon, Robert M. J.;
- Farias, Leandro A. E.;
- Hurley, Michael J.;
- Loyola, David E.;
- Vásquez, Rodrigo A.;
- Dobson, Richard;
- Guigó, Roderic;
- Cogram, Patricia
Publication type:
Article
A Subset of Cerebrospinal Fluid Proteins from a Multi-Analyte Panel Associated with Brain Atrophy, Disease Classification and Prediction in Alzheimer’s Disease.
Published in:
PLoS ONE, 2015, v. 10, n. 8, p. 1, doi. 10.1371/journal.pone.0134368
By:
- Khan, Wasim;
- Aguilar, Carlos;
- Kiddle, Steven J.;
- Doyle, Orla;
- Thambisetty, Madhav;
- Muehlboeck, Sebastian;
- Sattlecker, Martina;
- Newhouse, Stephen;
- Lovestone, Simon;
- Dobson, Richard;
- Giampietro, Vincent;
- Westman, Eric;
- Simmons, Andrew;
- null, null
Publication type:
Article
Plasma Based Markers of [<sup>11</sup>C] PiB-PET Brain Amyloid Burden.
Published in:
PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0044260
By:
- Kiddle, Steven John;
- Thambisetty, Madhav;
- Simmons, Andrew;
- Riddoch-Contreras, Joanna;
- Hye, Abdul;
- Westman, Eric;
- Pike, Ian;
- Ward, Malcolm;
- Johnston, Caroline;
- Lupton, Michelle Katharine;
- Lunnon, Katie;
- Soininen, Hilkka;
- Kłoszewska, Iwona;
- Tsolaki, Magda;
- Vellas, Bruno;
- Mecocci, Patrizia;
- Lovestone, Simon;
- Newhouse, Stephen;
- Dobson, Richard;
- Bush, Ashley I.
Publication type:
Article
Common Genetic Variation Near the Phospholamban Gene Is Associated with Cardiac Repolarisation: Meta- Analysis of Three Genome-Wide Association Studies.
Published in:
PLoS ONE, 2009, v. 4, n. 7, p. 1, doi. 10.1371/journal.pone.0006138
By:
- Nolte, Ilja M.;
- Wallace, Chris;
- Newhouse, Stephen J.;
- Waggott, Daryl;
- Jingyuan Fu;
- Soranzo, Nicole;
- Gwilliam, Rhian;
- Deloukas, Panos;
- Savelieva, Irina;
- Dongling Zheng;
- Dalageorgou, Chrysoula;
- Farrall, Martin;
- Samani, Nilesh J.;
- Connell, John;
- Brown, Morris;
- Dominiczak, Anna;
- Lathrop, Mark;
- Eleftheria Zeggini;
- Wain, Louise V.;
- Newton-Cheh, Christopher
Publication type:
Article
Targeting 160 Candidate Genes for Blood Pressure Regulation with a Genome-Wide Genotyping Array.
Published in:
PLoS ONE, 2009, v. 4, n. 6, p. 1, doi. 10.1371/journal.pone.0006034
By:
- Sõber, Siim;
- Org, Elin;
- Kepp, Katrin;
- Juhanson, Peeter;
- Eyheramendy, Susana;
- Gieger, Christian;
- Lichtner, Peter;
- Klopp, Norman;
- Veldre, Gudrun;
- Viigimaa, Margus;
- Döring, Angela;
- Putku, Margus;
- Kelgo, Piret;
- Shaw-Hawkins, Sue;
- Howard, Philip;
- Onipinla, Abiodun;
- Dobson, Richard J.;
- Newhouse, Stephen J.;
- Brown, Morris;
- Dominiczak, Anna
Publication type:
Article
Polymorphisms in the WNK1 Gene Are Associated with Blood Pressure Variation and Urinary Potassium Excretion.
Published in:
PLoS ONE, 2009, v. 4, n. 4, p. 1, doi. 10.1371/journal.pone.0005003
By:
- Newhouse, Stephen;
- Farrall, Martin;
- Wallace, Chris;
- Hoti, Mimoza;
- Burke, Beverley;
- Howard, Philip;
- Onipinla, Abiodun;
- Lee, Kate;
- Shaw-Hawkins, Sue;
- Dobson, Richard;
- Brown, Morris;
- Samani, Nilesh J.;
- Dominiczak, Anna F.;
- Connell, John M.;
- Lathrop, G. Mark;
- Kooner, Jaspal;
- Chambers, John;
- Elliott, Paul;
- Clarke, Robert;
- Collins, Rory
Publication type:
Article
C9orf72 intermediate expansions of 24–30 repeats are associated with ALS.
Published in:
Acta Neuropathologica Communications, 2019, v. 7, n. 1, p. N.PAG, doi. 10.1186/s40478-019-0724-4
By:
- Iacoangeli, Alfredo;
- Al Khleifat, Ahmad;
- Jones, Ashley R.;
- Sproviero, William;
- Shatunov, Aleksey;
- Opie-Martin, Sarah;
- Morrison, Karen E.;
- Shaw, Pamela J.;
- Shaw, Christopher E.;
- Fogh, Isabella;
- Dobson, Richard J.;
- Newhouse, Stephen J.;
- Al-Chalabi, Ammar
Publication type:
Article
The C9ORF72 expansion mutation is a common cause of ALS+/−FTD in Europe and has a single founder.
Published in:
European Journal of Human Genetics, 2013, v. 21, n. 1, p. 102, doi. 10.1038/ejhg.2012.98
By:
- Smith, Bradley N;
- Newhouse, Stephen;
- Shatunov, Aleksey;
- Vance, Caroline;
- Topp, Simon;
- Johnson, Lauren;
- Miller, Jack;
- Lee, Younbok;
- Troakes, Claire;
- Scott, Kirsten M;
- Jones, Ashley;
- Gray, Ian;
- Wright, Jamie;
- Hortobágyi, Tibor;
- Al-Sarraj, Safa;
- Rogelj, Boris;
- Powell, John;
- Lupton, Michelle;
- Lovestone, Simon;
- Sapp, Peter C
Publication type:
Article
Polygenic risk score analyses of symptoms and treatment response in an antipsychotic-naive first episode of psychosis cohort.
Published in:
Translational Psychiatry, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41398-018-0230-7
By:
- Santoro, Marcos Leite;
- Ota, Vanessa;
- de Jong, Simone;
- Noto, Cristiano;
- Spindola, Leticia M.;
- Talarico, Fernanda;
- Gouvea, Eduardo;
- Lee, Sang Hyuck;
- Moretti, Patricia;
- Curtis, Charles;
- Patel, Hamel;
- Newhouse, Stephen;
- Carvalho, Carolina Muniz;
- Gadelha, Ary;
- Cordeiro, Quirino;
- Bressan, Rodrigo Affonseca;
- Belangero, Sintia Iole;
- Breen, Gerome
Publication type:
Article
Genetic associations with radiological damage in rheumatoid arthritis: Meta-analysis of seven genome-wide association studies of 2,775 cases.
Published in:
PLoS ONE, 2019, v. 14, n. 10, p. 1, doi. 10.1371/journal.pone.0223246
By:
- Traylor, Matthew;
- Knevel, Rachel;
- Cui, Jing;
- Taylor, John;
- Harm-Jan, Westra;
- Conaghan, Philip G.;
- Cope, Andrew P.;
- Curtis, Charles;
- Emery, Paul;
- Newhouse, Stephen;
- Patel, Hamel;
- Steer, Sophia;
- Gregersen, Peter;
- Shadick, Nancy A.;
- Weinblatt, Michael E.;
- Van Der Helm-van Mil, Annette;
- Barrett, Jennifer H.;
- Morgan, Ann W.;
- Lewis, Cathryn M.;
- Scott, Ian C.
Publication type:
Article
Genetic and environmental risk factors for rheumatoid arthritis in a UK African ancestry population: the GENRA case--control study.
Published in:
Rheumatology, 2017, v. 56, n. 8, p. 1282, doi. 10.1093/rheumatology/kex048
By:
- Traylor, Matthew;
- Curtis, Charles;
- Patel, Hamel;
- Breen, Gerome;
- Sang Hyuck Lee;
- Xiaohui Xu;
- Newhouse, Stephen;
- Dobson, Richard;
- Steer, Sophia;
- Cope, Andrew P.;
- Markus, Hugh S.;
- Lewis, Cathryn M.;
- Scott, Ian C.
Publication type:
Article
Genome-Wide Association of Heroin Dependence in Han Chinese.
Published in:
PLoS ONE, 2016, v. 11, n. 12, p. 1, doi. 10.1371/journal.pone.0167388
By:
- Kalsi, Gursharan;
- Euesden, Jack;
- Coleman, Jonathan R. I.;
- Ducci, Francesca;
- Aliev, Fazil;
- Newhouse, Stephen J.;
- Liu, Xiehe;
- Ma, Xiaohong;
- Wang, Yingcheng;
- Collier, David A.;
- Asherson, Philip;
- Li, Tao;
- Breen, Gerome
Publication type:
Article
Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder.
Published in:
Communications Biology, 2018, v. 1, n. 1, p. N.PAG, doi. 10.1038/s42003-018-0155-y
By:
- de Jong, Simone;
- Diniz, Mateus Jose Abdalla;
- Saloma, Andiara;
- Gadelha, Ary;
- Santoro, Marcos L.;
- Ota, Vanessa K.;
- Noto, Cristiano;
- Curtis, Charles;
- Newhouse, Stephen J.;
- Patel, Hamel;
- Hall, Lynsey S.;
- O'Reilly, Paul F.;
- Belangero, Sintia I.;
- Bressan, Rodrigo A.;
- Breen, Gerome
Publication type:
Article
Calibrating Longitudinal Cognition in Alzheimer’s Disease Across Diverse Test Batteries and Datasets.
Published in:
Neuroepidemiology, 2015, v. 43, n. 3/4, p. 194, doi. 10.1159/000367970
By:
- Gross, alden L.;
- Sherva, Richard;
- Mukherjee, Shubhabrata;
- Newhouse, Stephen;
- Kauwe, John S.K.;
- Munsie, Leanne M.;
- Waterston, Leo B.;
- Bennett, David a.;
- Jones, Richard N.;
- Green, Robert C.;
- Crane, Paul K.
Publication type:
Article
Genome-wide scan identifies CDH13 as a novel susceptibility locus contributing to blood pressure determination in two European populations.
Published in:
Human Molecular Genetics, 2009, v. 18, n. 12, p. 2288, doi. 10.1093/hmg/ddp135
By:
- Org, Elin;
- Eyheramendy, Susana;
- Juhanson, Peeter;
- Gieger, Christian;
- Lichtner, Peter;
- Klopp, Norman;
- Veldre, Gudrun;
- Döring, Angela;
- Viigimaa, Margus;
- Sõber, Siim;
- Tomberg, Kärt;
- Eckstein, Gertrud;
- Kelgo, Piret;
- Rebane, Tiina;
- Shaw-Hawkins, Sue;
- Howard, Philip;
- Onipinla, Abiodun;
- Dobson, Richard J.;
- Newhouse, Stephen J.;
- Brown, Morris
Publication type:
Article
Haplotypes of the WNK1 gene associate with blood pressure variation in a severely hypertensive population from the British Genetics of Hypertension study.
Published in:
Human Molecular Genetics, 2005, v. 14, n. 13, p. 1805, doi. 10.1093/hmg/ddi187
By:
- Newhouse, Stephen J.;
- Wallace, Chris;
- Dobson, Richard;
- Mein, Charles;
- Pembroke, Janine;
- Farrall, Martin;
- Clayton, David;
- Brown, Morris;
- Samani, Nilesh;
- Dominiczak, Anna;
- Connell, John M.;
- Webster, John;
- Lathrop, G. Mark;
- Caulfield, Mark;
- Munroe, Patricia B.
Publication type:
Article
Quality control, imputation and analysis of genome-wide genotyping data from the Illumina HumanCoreExome microarray.
Published in:
Briefings in Functional Genomics, 2016, v. 15, n. 4, p. 298, doi. 10.1093/bfgp/elv037
By:
- Coleman, Jonathan R. I.;
- Euesden, Jack;
- Patel, Hamel;
- Folarin, Amos A.;
- Newhouse, Stephen;
- Breen, Gerome
Publication type:
Article
Genetic Predisposition to Increased Blood Cholesterol and Triglyceride Lipid Levels and Risk of Alzheimer Disease: A Mendelian Randomization Analysis.
Published in:
PLoS Medicine, 2014, v. 11, n. 9, p. 1, doi. 10.1371/journal.pmed.1001713
By:
- Proitsi, Petroula;
- Lupton, Michelle K.;
- Velayudhan, Latha;
- Newhouse, Stephen;
- Fogh, Isabella;
- Tsolaki, Magda;
- Daniilidou, Makrina;
- Pritchard, Megan;
- Kloszewska, Iwona;
- Soininen, Hilkka;
- Mecocci, Patrizia;
- Vellas, Bruno;
- Williams, Julie;
- Stewart, Robert;
- Sham, Pak;
- Lovestone, Simon;
- Powell, John F.
Publication type:
Article
SLC2A9 Is a High-Capacity Urate Transporter in Humans.
Published in:
PLoS Medicine, 2008, v. 5, n. 10, p. 1509, doi. 10.1371/journal.pmed.0050197
By:
- Caulfield, Mark J.;
- Munroe, Patricia B.;
- O'Neill, Deb;
- Witkowska, Kate;
- Charchar, Fadi J.;
- Doblado, Manuel;
- Evans, Sarah;
- Eyheramendy, Susana;
- Onipinla, Abiodun;
- Howard, Philip;
- Shaw-Hawkins, Sue;
- Dobson, Richard J.;
- Wallace, Chris;
- Newhouse, Stephen J.;
- Brown, Morris;
- Connell, John M.;
- Dominiczak, Anna;
- Farrall, Martin;
- Lathrop, G. Mark;
- Samani, Nilesh J.
Publication type:
Article
An MND/ALS phenotype associated with C9orf72 repeat expansion: Abundant p62-positive, TDP-43-negative inclusions in cerebral cortex, hippocampus and cerebellum but without associated cognitive decline.
Published in:
Neuropathology, 2012, v. 32, n. 5, p. 505, doi. 10.1111/j.1440-1789.2011.01286.x
By:
- Troakes, Claire;
- Maekawa, Satomi;
- Wijesekera, Lokesh;
- Rogelj, Boris;
- Siklós, László;
- Bell, Christopher;
- Smith, Bradley;
- Newhouse, Stephen;
- Vance, Caroline;
- Johnson, Lauren;
- Hortobágyi, Tibor;
- Shatunov, Aleksey;
- Al-Chalabi, Ammar;
- Leigh, Nigel;
- Shaw, Christopher E.;
- King, Andrew;
- Al-Sarraj, Safa
Publication type:
Article
Exome array analysis of adverse reactions to fluoropyrimidine-based therapy for gastrointestinal cancer.
Published in:
PLoS ONE, 2018, v. 13, n. 5, p. 1, doi. 10.1371/journal.pone.0188911
By:
- Traylor, Matthew;
- Walker, Jemma L.;
- Corrigan, Adele A.;
- Hernandez, Monica A.;
- Newhouse, Stephen J.;
- Folarin, Amos A.;
- Patel, Hamel;
- Ross, Paul J.;
- Sanderson, Jeremy D.;
- Spicer, James;
- Prescott, Natalie J.;
- Mathew, Christopher G.;
- Marinaki, Anthony M.;
- Lewis, Cathryn M.
Publication type:
Article
Trajectories of dementia-related cognitive decline in a large mental health records derived patient cohort.
Published in:
PLoS ONE, 2017, v. 12, n. 6, p. 1, doi. 10.1371/journal.pone.0178562
By:
- Baker, Elizabeth;
- Iqbal, Ehtesham;
- Johnston, Caroline;
- Broadbent, Matthew;
- Shetty, Hitesh;
- Stewart, Robert;
- Howard, Robert;
- Newhouse, Stephen;
- Khondoker, Mizanur;
- Dobson, Richard J. B.
Publication type:
Article

Found: 33