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- Title
Novel stroke risk reduction in atrial fibrillation: left atrial appendage occlusion with a focus on the Watchman closure device.
- Authors
Alipour, Arash; Wintgens, Lisette I. S.; Swaans, Martin J.; Balt, Jippe C.; Rensing, Benno J. W. M.; Boersma, Lucas V. A.
- Abstract
Atrial fibrillation (AF) remains an important clinical problem with severe complications such as stroke, which especially harms those with risk factors as calculated by the CHADS2 or CHA2DS2-VASc. Until now, no therapy has proven 100% effective against AF. Since the left atrial appendage (LAA) is the most prominent nonvalvular AF-related thromboembolic source and (novel) oral anticoagulant [(N)OAC] carries the hazard of bleeding, LAA occlusion may be an alternative, especially in patients who are ineligible for (N)OAC therapy. In this review, we discuss several LAA occlusion techniques with a focus on the Watchman device since this device is the most thoroughly studied device of all.
- Subjects
STROKE risk factors; ATRIAL fibrillation prevention; STROKE treatment; ANTICOAGULANTS; MITRAL valve; PHYSIOLOGY
- Publication
Vascular Health & Risk Management, 2017, Vol 13, p81
- ISSN
1176-6344
- Publication type
journal article
- DOI
10.2147/VHRM.S89213