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- Title
The effect of angiotensin receptor blockers on C-reactive protein and other circulating inflammatory indices in man.
- Authors
Alessandra del F; Cianchetti S; Celi A; Dell'omo G; Pedrinelli R; Del Fiorentino, Alessandra; Cianchetti, Silvana; Celi, Alessandro; Dell'Omo, Giulia; Pedrinelli, Roberto
- Abstract
Anti-inflammatory properties may contribute to the pharmacological effects of angiotensin II receptor blockers (ARBs), a leading therapeutic class in the management of hypertension and related cardiovascular and renal diseases. That possibility, supported by consistent evidence from in-vitro and animal studies showing pro-inflammatory properties of angiotensin II, has been evaluated clinically by measuring the effect of ARBs on C-reactive protein and other circulating indices of inflammation (e-selectin, adhesion molecules, interleukin-6, tissue necrosis factor-alpha, monocyte chemoattractant protein-1) of potential clinical relevance, a body of evidence that this paper aims to review.
- Publication
Vascular Health & Risk Management, 2009, Vol 5, p233
- ISSN
1176-6344
- Publication type
journal article