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- Title
Role of Drosophila in Human Disease Research 2.0.
- Authors
Yamaguchi, Masamitsu; Yamamoto, Shinya
- Abstract
Yamaguchi et al. summarized pioneering studies using I Drosophila i models that linked ALS and CMT to epigenetic regulation associated with post-translational histone modifications and noncoding RNAs [[8]]. Indeed, the authors discuss that genetic approaches using I Drosophila i models identified several epigenetic regulators as important modifiers of phenotypes seen in ALS and CMT model flies. Further characterization of these factors in relation to these diseases would be an important future direction, not only for ALS and CMT research but also for studies related to other types of neurological and neurodegenerative disorders. The fruit fly I Drosophila melanogaster i is a highly tractable animal model to study various human diseases [[1]].
- Subjects
DROSOPHILA; MEDICAL sciences; HUMAN experimentation; MEDICAL societies; FRUIT flies; LINCRNA; TRANSFER RNA
- Publication
International Journal of Molecular Sciences, 2022, Vol 23, Issue 8, p4203
- ISSN
1661-6596
- Publication type
Editorial
- DOI
10.3390/ijms23084203