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- Title
A Missing Dimension in Measures of Vaccination Impacts.
- Authors
Gomes, M. Gabriela M.; Lipsitch, Marc; Wargo, Andrew R.; Kurath, Gael; Rebelo, Carlota; Medley, Graham F.; Coutinho, Antonio
- Abstract
The article suggests a shift to a dose-dimension paradigm in the development of vaccines for infectious diseases. Topics covered include a model of pathogen transmission for exploring population effects of protection by a vaccine against infection, dose-infectivity curves, and classification of beta distribution shapes based on polarization.
- Subjects
DOSAGE forms of drugs; VACCINES; PREVENTION of communicable diseases; INFECTIOUS disease transmission; VACCINATION
- Publication
PLoS Pathogens, 2014, Vol 10, Issue 3, p1
- ISSN
1553-7366
- Publication type
Article
- DOI
10.1371/journal.ppat.1003849