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Pharmacokinetic/Pharmacodynamic Evaluation of a New Purine-2,6-Dione Derivative in Rodents with Experimental Autoimmune Diseases.
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- Pharmaceutics, 2022, v. 14, n. 5, p. 1090, doi. 10.3390/pharmaceutics14051090
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- Article
PK/PD Modeling of the PDE7 Inhibitor—GRMS-55 in a Mouse Model of Autoimmune Hepatitis.
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- Pharmaceutics, 2021, v. 13, n. 5, p. 597, doi. 10.3390/pharmaceutics13050597
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- Article
Pan-Phosphodiesterase Inhibitors Attenuate TGF-β-Induced Pro-Fibrotic Phenotype in Alveolar Epithelial Type II Cells by Downregulating Smad-2 Phosphorylation.
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- Pharmaceuticals (14248247), 2022, v. 15, n. 4, p. N.PAG, doi. 10.3390/ph15040423
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- Article
A Novel, Pan-PDE Inhibitor Exerts Anti-Fibrotic Effects in Human Lung Fibroblasts via Inhibition of TGF-β Signaling and Activation of cAMP/PKA Signaling.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 11, p. 4008, doi. 10.3390/ijms21114008
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- Article
Correction to: Comparative Assessment of the New PDE7 Inhibitor – GRMS-55 and Lisofylline in Animal Models of Immune-Related Disorders: A PK/PD Modeling Approach.
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- 2020
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- Correction Notice
Comparative Assessment of the New PDE7 Inhibitor – GRMS-55 and Lisofylline in Animal Models of Immune-Related Disorders: A PK/PD Modeling Approach.
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- Pharmaceutical Research, 2020, v. 37, n. 2, p. 1, doi. 10.1007/s11095-019-2727-z
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- Article
Determination of ligand efficiency indices in a group of 7H‐purine‐2,6‐dione derivatives with psychotropic activity using micellar electrokinetic chromatography.
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- Electrophoresis, 2018, v. 39, n. 19, p. 2446, doi. 10.1002/elps.201800156
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- Article
Aminoalkyl Derivatives of 8-Alkoxypurine-2,6-diones: Multifunctional 5-HT<sub>1A</sub>/5-HT<sub>7</sub> Receptor Ligands and PDE Inhibitors with Antidepressant Activity.
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- Archiv der Pharmazie, 2016, v. 349, n. 12, p. 889, doi. 10.1002/ardp.201600260
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- Article
Structure-5-HT/D<sub>2</sub> Receptor Affinity Relationship in a New Group of 1-Arylpiperazynylalkyl Derivatives of 8-Dialkylamino-3,7-dimethyl-1 H-purine-2,6(3 H,7 H)-dione.
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- Archiv der Pharmazie, 2016, v. 349, n. 10, p. 774, doi. 10.1002/ardp.201600162
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- Article
New Arylpiperazinylalkyl Derivatives of 8-Alkoxy-purine-2,6-dione and Dihydro[1,3]oxazolo[2,3- f]purinedione Targeting the Serotonin 5-HT<sub>1A</sub>/5-HT<sub>2A</sub>/5-HT<sub>7</sub> and Dopamine D<sub>2</sub> Receptors.
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- Archiv der Pharmazie, 2015, v. 348, n. 4, p. 242, doi. 10.1002/ardp.201500015
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- Article
Structure-5-HT Receptor Affinity Relationship in a New Group of 7-Arylpiperazynylalkyl and 7-Tetrahydroisoquinolinylalkyl Derivatives of 8-Amino-1,3-dimethyl-1 H-purine-2,6(3 H,7 H)-dione.
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- Archiv der Pharmazie, 2015, v. 348, n. 4, p. 229, doi. 10.1002/ardp.201400392
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- Article
Preliminary study on application of impregnated synthetic peptide TLC stationary phases for the pre-screening of 5-HT<sub>1A</sub> ligands.
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- Biomedical Chromatography, 2003, v. 17, n. 5, p. 312, doi. 10.1002/bmc.224
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- Article
ANALGESIC AND ANTI-INFLAMMATORY ACTIVITY OF NEW ANALOGS OF HC-030031: A TRPA1 CHANNEL ANTAGONIST.
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- Acta Poloniae Pharmaceutica, 2020, v. 77, n. 1, p. 113, doi. 10.32383/appdr/117836
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- Article
In Vitro Biotransformation, Safety, and Chemopreventive Action of Novel 8-Methoxy-Purine-2,6-Dione Derivatives.
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- Applied Biochemistry & Biotechnology, 2018, v. 184, n. 1, p. 124, doi. 10.1007/s12010-017-2527-z
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- Article
Antiplatelet Effects of Selected Xanthine-Based Adenosine A 2A and A 2B Receptor Antagonists Determined in Rat Blood.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 17, p. 13378, doi. 10.3390/ijms241713378
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- Article
Synthesis of 8-alkoxy-1,3-dimethyl-2, 6-dioxopurin-7-yl-substituted acetohydrazides and butanehydrazides as analgesic and anti-inflammatory agents.
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- Heterocyclic Communications, 2015, v. 21, n. 5, p. 273, doi. 10.1515/hc-2015-0100
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- Article
N-(4-Arylpiperazinoalkyl)acetamide derivatives of 1,3- and 3,7-dimethyl-1 H-purine-2,6(3 H,7 H)-diones and their 5-HT<sub>6</sub>, 5-HT<sub>7</sub>, and D<sub>2</sub> receptors affinity.
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- Heterocyclic Communications, 2015, v. 21, n. 1, p. 13, doi. 10.1515/hc-2014-0200
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- Article