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- Title
Cancer biology: Doing more with less.
- Abstract
The article reports on the result of a study conducted by Markus Bredel of the Northwestern University Feinberg School of Medicine in Chicago, Illinois, and his colleagues about the implication of the expression of tumour-suppressor gene ANXA7. They found that the expression of ANXA7, which is located on chromosome 10, is reduced in these cells. They reveal that in cell cultures, when ANXA7 protein levels dropped, EGFR levels rose and the tumour-generating potential of these cells increased.
- Subjects
TUMORS; TUMOR suppressor genes; GENE expression; CHROMOSOMES; CELL culture; BREDEL, Markus
- Publication
Nature, 2009, Vol 460, Issue 7254, p438
- ISSN
0028-0836
- Publication type
Article
- DOI
10.1038/460438e