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Two postprocessing techniques for the elimination of background autofluorescence for fluorescence lifetime imaging microscopy.
- Published in:
- Journal of Biomedical Optics, 2008, v. 13, n. 1, p. 14008, doi. 10.1117/1.2837169
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- Publication type:
- Article
Not all plaques are created equal: Uncovering a unique molecular signature in Alzheimer's disease.
- Published in:
- Brain & Neuroscience Advances, 2024, p. 1, doi. 10.1177/23982128241280001
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- Publication type:
- Article
Apolipoprotein E isoform does not influence trans-synaptic spread of tau pathology in a mouse model.
- Published in:
- Brain & Neuroscience Advances, 2023, p. 1, doi. 10.1177/23982128231191046
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- Publication type:
- Article
Reducing voltage-dependent potassium channel Kv3.4 levels ameliorates synapse loss in a mouse model of Alzheimer's disease.
- Published in:
- Brain & Neuroscience Advances, 2022, p. 1, doi. 10.1177/23982128221086464
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- Publication type:
- Article
Reducing voltage-dependent potassium channel Kv3.4 levels ameliorates synapse loss in a mouse model of Alzheimer's disease.
- Published in:
- Brain & Neuroscience Advances, 2022, v. 5, p. 1, doi. 10.1177/23982128221086464
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- Publication type:
- Article
Creating and Validating a DNA Methylation-Based Proxy for Interleukin-6.
- Published in:
- 2021
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- Publication type:
- journal article
Trajectories of inflammatory biomarkers over the eighth decade and their associations with immune cell profiles and epigenetic ageing.
- Published in:
- Clinical Epigenetics, 2018, v. 10, n. 1, p. N.PAG, doi. 10.1186/s13148-018-0585-x
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- Publication type:
- Article
A study to determine the mechanisms underlying changes in synaptic vesicle glycoprotein 2A density in Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.082561
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- Publication type:
- Article
Lowering Synaptogyrin‐3 Expression Rescues Tau‐Induced Memory Deficits and Synaptic Loss in the Presence of Microglial Activation.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 4, p. 1, doi. 10.1002/alz.064090
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- Publication type:
- Article
Synaptic oligomeric Tau is an early event in tau‐affected brain regions in Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 4, p. 1, doi. 10.1002/alz.063598
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- Publication type:
- Article
A role for astrocytes and microglia in synapse loss in Alzheimer’s disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.052532
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- Publication type:
- Article
Proceedings from the Fourth International Symposium on σ-2 Receptors: Role in Health and Disease.
- Published in:
- eNeuro, 2020, v. 7, n. 6, p. 1, doi. 10.1523/ENEURO.0317-20.2020
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- Publication type:
- Article
High neural activity accelerates the decline of cognitive plasticity with age in Caenorhabditis elegans.
- Published in:
- eLife, 2020, p. 1, doi. 10.7554/eLife.59711
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- Publication type:
- Article
INTERACTIONS OF ABETA AND TAU IN SYNAPSE LOSS.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P1219, doi. 10.1016/j.jalz.2017.07.399
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- Publication type:
- Article
Amyloid-beta oligomerization is associated with the generation of a typical peptide fragment fingerprint.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, n. 9, p. 996, doi. 10.1016/j.jalz.2016.03.011
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- Publication type:
- Article
TAU SPREADING AND TOXICITY.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P269, doi. 10.1016/j.jalz.2016.06.2381
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- Publication type:
- Article
Lack of endogenous tau permits tau spreading and protects against tau toxicity in transgenic mice.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P186, doi. 10.1016/j.jalz.2015.07.159
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- Publication type:
- Article
A transgenic model of the earliest stage of Alzheimer's disease
- Published in:
- 2010
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- Publication type:
- Abstract
P1-486: Decreased neuronal activity in APP transgenic mice measured via dendritic protein synthesis
- Published in:
- 2008
- By:
- Publication type:
- Abstract
Amyloid accelerates tau propagation and toxicity in a model of early Alzheimer's disease.
- Published in:
- Acta Neuropathologica Communications, 2015, v. 3, n. 1, p. 1, doi. 10.1186/s40478-015-0199-x
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- Publication type:
- Article
Post-mortem brain analyses of the Lothian Birth Cohort 1936: extending lifetime cognitive and brain phenotyping to the level of the synapse.
- Published in:
- Acta Neuropathologica Communications, 2015, v. 3, n. 1, p. 1, doi. 10.1186/s40478-015-0232-0
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- Publication type:
- Article
Amyloid accelerates tau propagation and toxicity in a model of early Alzheimer's disease.
- Published in:
- Acta Neuropathologica Communications, 2015, v. 3, n. 1, p. 1, doi. 10.1186/s40478-015-0199-x
- By:
- Publication type:
- Article
Alzheimer's Therapeutics Targeting Amyloid Beta 1–42 Oligomers II: Sigma-2/PGRMC1 Receptors Mediate Abeta 42 Oligomer Binding and Synaptotoxicity.
- Published in:
- PLoS ONE, 2014, v. 9, n. 11, p. 1, doi. 10.1371/journal.pone.0111899
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- Publication type:
- Article
Synapse Density and Dendritic Complexity Are Reduced in the Prefrontal Cortex following Seven Days of Forced Abstinence from Cocaine Self-Administration.
- Published in:
- PLoS ONE, 2014, v. 9, n. 7, p. 1, doi. 10.1371/journal.pone.0102524
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- Publication type:
- Article
Tau Causes Synapse Loss without Disrupting Calcium Homeostasis in the rTg4510 Model of Tauopathy.
- Published in:
- PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0080834
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- Publication type:
- Article
Apolipoprotein E: Isoform Specific Differences in Tertiary Structure and Interaction with Amyloid-β in Human Alzheimer Brain.
- Published in:
- PLoS ONE, 2011, v. 6, n. 1, p. 1, doi. 10.1371/journal.pone.0014586
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- Publication type:
- Article
Comparative profiling of the synaptic proteome from Alzheimer's disease patients with focus on the APOE genotype.
- Published in:
- Acta Neuropathologica Communications, 2019, v. 7, n. 1, p. 1, doi. 10.1186/s40478-019-0847-7
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- Publication type:
- Article
Conditional Deletion of PDK1 in the Forebrain Causes Neuron Loss and Increased Apoptosis during Cortical Development.
- Published in:
- Frontiers in Cellular Neuroscience, 2017, p. 1, doi. 10.3389/fncel.2017.00330
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- Publication type:
- Article
A Reporter of Local Dendritic Translocation Shows Plaque-Related Loss of Neural System Function in APP-Transgenic Mice.
- Published in:
- Journal of Neuroscience, 2009, v. 29, n. 40, p. 12636, doi. 10.1523/JNEUROSCI.1948-09.2009
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- Publication type:
- Article
In Vivo Imaging Reveals Dissociation between Caspase Activation and Acute Neuronal Death in Tangle-Bearing Neurons.
- Published in:
- Journal of Neuroscience, 2008, v. 28, n. 4, p. 862, doi. 10.1523/JNEUROSCI.3072-08.2008
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- Publication type:
- Article
Removing endogenous tau does not prevent tau propagation yet reduces its neurotoxicity.
- Published in:
- EMBO Journal, 2015, v. 34, n. 24, p. 3028, doi. 10.15252/embj.201592748
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- Publication type:
- Article
Caspase activation precedes and leads to tangles.
- Published in:
- Nature, 2010, v. 464, n. 7292, p. 1201, doi. 10.1038/nature08890
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- Publication type:
- Article
Rapid appearance and local toxicity of amyloid-β plaques in a mouse model of Alzheimer’s disease.
- Published in:
- Nature, 2008, v. 451, n. 7179, p. 720, doi. 10.1038/nature06616
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- Publication type:
- Article
Altered amyloid-β structure markedly reduces gliosis in the brain of mice harboring the Uppsala APP deletion.
- Published in:
- Acta Neuropathologica Communications, 2024, v. 12, p. 1, doi. 10.1186/s40478-024-01734-x
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- Publication type:
- Article
Synaptic proteomics reveal distinct molecular signatures of cognitive change and C9ORF72 repeat expansion in the human ALS cortex.
- Published in:
- Acta Neuropathologica Communications, 2022, v. 10, n. 1, p. 1, doi. 10.1186/s40478-022-01455-z
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- Publication type:
- Article
Childhood intelligence attenuates the association between biological ageing and health outcomes in later life.
- Published in:
- Translational Psychiatry, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41398-019-0657-5
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- Publication type:
- Article
Synaptic gene expression changes in frontotemporal dementia due to the MAPT 10 + 16 mutation.
- Published in:
- Neuropathology & Applied Neurobiology, 2024, v. 50, n. 4, p. 1, doi. 10.1111/nan.13006
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- Publication type:
- Article
Apolipoprotein E4 effects in Alzheimer’s disease are mediated by synaptotoxic oligomeric amyloid-β.
- Published in:
- Brain: A Journal of Neurology, 2012, v. 135, n. 7, p. 2155, doi. 10.1093/brain/aws127
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- Publication type:
- Article
Brain interstitial oligomeric amyloid β increases with age and is resistant to clearance from brain in a mouse model of Alzheimer's disease.
- Published in:
- FASEB Journal, 2013, v. 27, n. 8, p. 3239, doi. 10.1096/fj.13-229666
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- Publication type:
- Article
Tau association with synaptic vesicles causes presynaptic dysfunction.
- Published in:
- Nature Communications, 2017, v. 8, n. 5, p. 15295, doi. 10.1038/ncomms15295
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- Publication type:
- Article
Alzheimer's disease‐like neuropathology in three species of oceanic dolphin.
- Published in:
- European Journal of Neuroscience, 2023, v. 57, n. 7, p. 1161, doi. 10.1111/ejn.15900
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- Publication type:
- Article
Associations between cerebrospinal fluid markers and cognition in ageing and dementia: A systematic review.
- Published in:
- European Journal of Neuroscience, 2022, v. 56, n. 9, p. 5650, doi. 10.1111/ejn.15656
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- Publication type:
- Article
Alzheimer's disease and related dementias: From risk factors to disease pathogenesis.
- Published in:
- European Journal of Neuroscience, 2022, v. 56, n. 9, p. 5337, doi. 10.1111/ejn.15857
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- Publication type:
- Article
Potential neurobiological links between social isolation and Alzheimer's disease risk.
- Published in:
- European Journal of Neuroscience, 2022, v. 56, n. 9, p. 5397, doi. 10.1111/ejn.15373
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- Publication type:
- Article
Maintained memory and long‐term potentiation in a mouse model of Alzheimer's disease with both amyloid pathology and human tau.
- Published in:
- European Journal of Neuroscience, 2021, v. 53, n. 2, p. 637, doi. 10.1111/ejn.14918
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- Publication type:
- Article
Human tau increases amyloid β plaque size but not amyloid β-mediated synapse loss in a novel mouse model of Alzheimer's disease.
- Published in:
- European Journal of Neuroscience, 2016, v. 44, n. 12, p. 3056, doi. 10.1111/ejn.13442
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- Publication type:
- Article
Tau-amyloid interactions in the rTgTauEC model of early Alzheimer's disease suggest amyloid-induced disruption of axonal projections and exacerbated axonal pathology.
- Published in:
- Journal of Comparative Neurology, 2013, v. 521, n. 18, p. 4236, doi. 10.1002/cne.23411
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- Publication type:
- Article
Synaptic alterations in the rTg4510 mouse model of tauopathy.
- Published in:
- Journal of Comparative Neurology, 2013, v. 521, n. 6, p. 1334, doi. 10.1002/cne.23234
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- Publication type:
- Article
Spread of tau down neural circuits precedes synapse and neuronal loss in the rTgTauEC mouse model of early Alzheimer's disease.
- Published in:
- Synapse, 2017, v. 71, n. 6, p. n/a, doi. 10.1002/syn.21965
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- Publication type:
- Article
Differential effect of three-repeat and four-repeat tau on mitochondrial axonal transport.
- Published in:
- Journal of Neurochemistry, 2009, v. 111, n. 2, p. 417, doi. 10.1111/j.1471-4159.2009.06316.x
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- Publication type:
- Article