We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Attempts to Demonstrate Peptide Localization and Secretion in Primary Cell Cultures of Fetal Rat Hypothalamus.
- Authors
Denizeau, Francine; Dubé, Donald; Antakly, Tony; Lemay, André; Parent, André; Pelletier, Georges; Labrie, Fernand
- Abstract
Primary cultures of dispersed hypothalamic cells were prepared from 18- to 19-day-old rat fetuses. Morphological studies revealed two types of cells having typical glial and neuronal appearances. Immunostaining of cells in culture was positive for neurophysin. The incubation medium contained radioimmunoassayable luteinizing hormone-releasing hormone, vasopressin, β-endorphin and adrenocorticotropin hormone. The present data suggest that hypothalamic cells in primary culture secrete immunoreactive hormones or peptides; however, they do not seem to store significant amounts of these peptides. Copyright © 1981 S. Karger AG, Basel
- Publication
Neuroendocrinology, 1981, Vol 32, Issue 2, p96
- ISSN
0028-3835
- Publication type
Article
- DOI
10.1159/000123138