We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Mid-term outcome of severe tricuspid regurgitation: are there any differences according to mechanism and severity?
- Authors
Santoro, Ciro; Castillo, Alvaro Marco del; González-Gómez, Ariana; Monteagudo, Juan Manuel; Hinojar, Rocio; Lorente, Alvaro; Abellás, María; Vieitez, Jose Maria; Martìn, Ana Garcia; Rojo, Eduardo Casas; Ruíz, Soledad; Barrios, Vivencio; Moya, Jose Luis; Jimenez-Nacher, Jose Julio; Gomez, Jose Luis Zamorano; Fernández-Golfín, Covadonga
- Abstract
Aims Patients with significant tricuspid regurgitation (TR) addressed according the new classification in torrential TR may have different prognosis compared with just severe TR patients. We sought to determine distribution and mechanism of consecutive severe TR patients, in accordance with aetiology and severity by applying the new proposed classification scheme and their long-term outcomes. Methods and results Between January and December 2013, 249 patients with significant TR referred to the cardiac imaging unit (mean age 79.9 ± 10.2 years; 29.8% female) were included. Patients were divided according to aetiology in six groups, and TR severity was reclassified into severe, massive, and torrential TR. The follow-up period was of 313 ± 103 days. When considering cardiovascular mortality, patients in the massive/torrential group showed the highest number of events (P < 0.007). Patients with TR due to pulmonary diseases had the worst prognosis according to different aetiology. Noteworthy, the best predictors for the combined endpoint [cardiovascular mortality and readmission admission for heart failure (HF)] were TR severity according to the new classification [hazard ratio (HR) 2.48, 95% confidence interval (CI) 1.25–4.93] and clinical scores such as New York Heart Association classification and congestive status (HR 1.78, 95% CI 1.28–2.49; HR 2.08, 95% CI 1.06–4.06, respectively). Conclusion Patients with massive/torrential TR and patients with comorbidities, especially pulmonary disease, were identified as populations at higher risk of death and readmission for HF. New classification scheme and clinical assessment may establish who may benefit the most of intensive therapeutic treatments and intervention on the tricuspid valve.
- Subjects
CARDIOVASCULAR disease related mortality; CARDIOVASCULAR disease diagnosis; CONFIDENCE intervals; HEART valve diseases; TREATMENT effectiveness; SEVERITY of illness index; DESCRIPTIVE statistics
- Publication
European Heart Journal - Cardiovascular Imaging, 2019, Vol 20, Issue 9, p1035
- ISSN
2047-2404
- Publication type
Article
- DOI
10.1093/ehjci/jez024