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- Title
Risk Factors for Acute Non-A, Non-B Hepatitis and their Relationship to Antibodies for Hepatitis C Virus: A Case-Control Study.
- Authors
Mele, Alfonso; Sagliocca, Luciano; Manzillo, Giuseppe; Converti, Francesco; Amoroso, Pietro; Stazi, Maria Antonietta; Ferrigno, Luigina; Rapicetta, Mariella; Franco, Elisabetta; Adamo, Brunella; Palumbo, Filippo; Sbreglia, Costanza; Panà, Augusto; Pasquini, Paolo
- Abstract
A case-control study was carried out comparing 333 case subjects with non-A non-B hepatitis and 1095 hospital control subjects. Of 333 case subjects, 197 (59%) were positive for hepatitis C antibody (anti-HCV). Excluding blood transfusion and intravenous drug use, surgical intervention and dental therapy were strongly associated with anti-HCV-positive cases: in particular, obstetric and gynecology surgical intervention was found to be strongly associated with HCV positivity (odds ratio [OR]=32; 95% confidence interval [CI]=7, 147). Raw shellfish consumption was a risk factor for antiHCV-negative case (OR =2.2;95% CI =1.0,5.1), thus suggesting an enterically transmitted virus in sporadic non-A, non-B hepatitis in Italy.
- Subjects
HEPATITIS A; HEPATITIS B; HEPATITIS C virus; IMMUNOGLOBULINS; BLOOD transfusion; OBSTETRICS; HOSPITALS
- Publication
American Journal of Public Health, 1994, Vol 84, Issue 10, p1640
- ISSN
0090-0036
- Publication type
Article
- DOI
10.2105/AJPH.84.10.1640