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- Title
Genes predict village of origin in rural Europe.
- Authors
O'Dushlaine, Colm; McQuillan, Ruth; Weale, Michael E.; Crouch, Daniel J. M.; Johansson, Åsa; Aulchenko, Yurii; Franklin, Christopher S.; Pola&;#x0161;ek, Ozren; Fuchsberger, Christian; Corvin, Aiden; Hicks, Andrew A.; Vitart, Veronique; Hayward, Caroline; Wild, Sarah H.; Meitinger, Thomas; van Duijn, Cornelia M.; Gyllensten, Ulf; Wright, Alan F.; Campbell, Harry; Pramstaller, Peter P.
- Abstract
The genetic structure of human populations is important in population genetics, forensics and medicine. Using genome-wide scans and individuals with all four grandparents born in the same settlement, we here demonstrate remarkable geographical structure across 8-30 km in three different parts of rural Europe. After excluding close kin and inbreeding, village of origin could still be predicted correctly on the basis of genetic data for 89-100% of individuals.
- Subjects
EUROPE; GENETIC research; POPULATION genetics; HEREDITY; RURAL population
- Publication
European Journal of Human Genetics, 2010, Vol 18, Issue 11, p1269
- ISSN
1018-4813
- Publication type
Article
- DOI
10.1038/ejhg.2010.92