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- Title
Highly clarithromycin-resistant Helicobacter pylori infection in asymptomatic children from a rural community of Cajamarca-Peru.
- Authors
Aguilar-Luis, Miguel Angel; Palacios-Cuervo, Fernando; Espinal-Reyes, Fátima; Calderón-Rivera, Andrea; Levy-Blitchtein, Saúl; Palomares-Reyes, Carlos; Silva-Caso, Wilmer; Zavaleta-Gavidia, Victor; Bazán-Mayra, Jorge; Cornejo-Tapia, Angela; del Valle-Mendoza, Juana; del Valle, Luis J.
- Abstract
Objective: The objective of this study was to determine the prevalence of clarithromycin-resistant Helicobacter pylori in asymptomatic children in a rural community of Cajamarca (northern Peru). Results: Helicobacter pylori was detected in 17.2% (49/285) of the samples. Unboiled water consumption the most frequent associated factor in patients with positive PCR for H. pylori infection (93.9%). Clarithromycin resistant mutations were found in 79.6% (39/49) of the positive samples for H. pylori. The most frequent mutation was A2142G (46.9%), followed by the double-mutation A2142G–A2143G (28.6%).
- Subjects
CLARITHROMYCIN; HELICOBACTER pylori infections; DRUG resistance in bacteria; POLYMERASE chain reaction; BACTERIAL mutation
- Publication
BMC Research Notes, 2018, Vol 11, Issue 1, pN.PAG
- ISSN
1756-0500
- Publication type
Article
- DOI
10.1186/s13104-018-3919-z