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- Title
Hepatocellular carcinoma in Chinese males and females. Possible causes for the male predominance.
- Authors
Lai, Ching-Lung; Gregory, Peter B.; Wu, Pui-Chee; Lok, Anna S. F.; Wong, Kai-Ping; Ng, Matthew M. T.; Lai, C L; Gregory, P B; Wu, P C; Lok, A S; Wong, K P; Ng, M M
- Abstract
The male-female ratio in 186 hepatocellular carcinoma (HCC) Chinese patients was 5:1. The clinical presentation, biochemical parameters, and histologic findings were the same in both sexes except for a higher proportion of underlying cirrhosis (P = 0.02), and spider naevi (P = 0.04) in the men. There were also more smokers and alcohol drinkers among the men. Over 75% of both sexes were positive for the hepatitis B surface antigen. The possible contributory factors to the predominance of males to females in HCC included: the association with the hepatitis B virus, the higher proportion of male cirrhotics, smoking, and alcohol drinking. The survival probability for both sexes was equally poor; the median survival was 8 weeks for males and 10 weeks for females.
- Publication
Cancer (0008543X), 1987, Vol 60, Issue 5, p1107
- ISSN
0008-543X
- Publication type
journal article
- DOI
10.1002/1097-0142(19870901)60:5<1107::AID-CNCR2820600531>3.0.CO;2-O