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- Title
SIVdrl detection in captive mandrills: are mandrills infected with a third strain of simian immunodeficiency virus?
- Authors
Van der Kuyl, Antoinette C.; Van den Burg, Remco; Hoyer, Mark J.; Gruters, Rob A.; Osterhaus, Albert D. M. E.; Berkhout, Ben
- Abstract
A pol-fragment of simian immunodeficiency virus (SIV) that is highly related to SIVdr1-pol from drill monkeys (Mandrillus leucophaeus) was detected in two mandrills (Mandrillus sphinx) from Amsterdam Zoo. These captivity-born mandrills had never been in contact with drill monkeys, and were unlikely to be hybrids. Their mitochondrial haplotype suggested that they descended from founder animals in Cameroon or northern Gabon, close to the habitat of the drill. SIVdr1 has once before been found in a wild-caught mandrill from the same region, indicating that mandrills are naturally infected with a SIVdr1-like virus. This suggests that mandrills are the first primate species to be infected with three strains of SIV: SIVmnd1, SIVmnd2, and SIVdr1.
- Subjects
AMSTERDAM (Netherlands); NETHERLANDS; VIRUSES; MONKEYS; ZOOS
- Publication
Retrovirology, 2004, Vol 1, p1
- ISSN
1742-4690
- Publication type
Article
- DOI
10.1186/1742-4690-1-36